Figures & data
Table 1 Dimensions and weight of fabricated small-size matrix intravaginal rings
Table 2 Dimensions of fabricated PU-93A and PU-60D res-intravaginal ring segments
Figure 1 Drug-free and hydroxychloroquine (HCQ)-loaded matrix and reservoir intravaginal rings (IVRs).
Abbreviation: res-IVRs, reservoir intravaginal rings; XD, cross-sectional diameter; OD, outer diameter; mm, millimeter; PU, polyether urethane.
![Figure 1 Drug-free and hydroxychloroquine (HCQ)-loaded matrix and reservoir intravaginal rings (IVRs).](/cms/asset/6fa3c34e-2df7-473e-9057-3ffe3f3204be/dddt_a_71352_f0001_c.jpg)
Figure 2 In vitro release of hydroxychloroquine (HCQ) from matrix intravaginal rings (IVRs) and res-IVRs.
Abbreviations: res-IVRs, reservoir intravaginal rings; PVP, polyvinylpyrrolidone; PVA, poly(vinyl alcohol).
![Figure 2 In vitro release of hydroxychloroquine (HCQ) from matrix intravaginal rings (IVRs) and res-IVRs.](/cms/asset/5f56d161-d558-4b21-b2ef-bffa5d3e6ebe/dddt_a_71352_f0002_c.jpg)
Figure 3 PU-93A matrix intravaginal ring accelerated stability test.
![Figure 3 PU-93A matrix intravaginal ring accelerated stability test.](/cms/asset/d727ca6f-fe3e-480d-9aaf-d09ab2a7555b/dddt_a_71352_f0003_b.jpg)
Figure 4 Swelling test of PU-93A matrix intravaginal ring segments.
Abbreviations: PVP, polyvinylpyrrolidone; PVA, poly(vinyl alcohol).
![Figure 4 Swelling test of PU-93A matrix intravaginal ring segments.](/cms/asset/81d930fc-9d1a-4f65-bd61-99efc3dc338c/dddt_a_71352_f0004_c.jpg)
Figure 5 In vitro biocompatibility evaluations of hot-melt intravaginal ring segments.
Abbreviations: N, negative control; P, positive control; PVP, polyvinylpyrrolidone; PVA, poly(vinyl alcohol).
![Figure 5 In vitro biocompatibility evaluations of hot-melt intravaginal ring segments.](/cms/asset/a5c62b62-36ba-4177-8905-23853b0db286/dddt_a_71352_f0005_b.jpg)