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Review

Update on the usage and safety of epinephrine auto-injectors, 2017

&
Pages 9-18 | Published online: 21 Mar 2017

Figures & data

Figure 1 Criteria that increase the likelihood of anaphylaxis.

Note: Adapted from Simons FE, Ardusso LR, Bilò MB, et al. World allergy organization guidelines for the assessment and management of anaphylaxis. World Allergy Organ J. 2011;4(2):13–37.Citation2
Figure 1 Criteria that increase the likelihood of anaphylaxis.

Figure 2 Pharmacological effects of epinephrine in the treatment of anaphylaxis.

Figure 2 Pharmacological effects of epinephrine in the treatment of anaphylaxis.

Figure 3 Self-administration of an epinephrine auto-injector.

Figure 3 Self-administration of an epinephrine auto-injector.

Figure 4 Comparison of the (A) old-look and (B) new-look (right) EpiPen® Auto-Injector (Mylan Specialty L.P., Canonsburg, PA, USA).

Note: The EpiPen Auto-Injector was redesigned in 2011 to include safety features such as the orange needle sheath.
Figure 4 Comparison of the (A) old-look and (B) new-look (right) EpiPen® Auto-Injector (Mylan Specialty L.P., Canonsburg, PA, USA).

Figure 5 Proposed child restraint options for the administration of an epinephrine auto-injector.

Note: Reprinted from The Journal of Allergy and Clinical Immunology: In Practice, Volume 4/edition 3, Brown JC, Tuuri RE, Lacerations and embedded needles due to EpiPen use in children, Pages 549–551, Copyright 2016, with permission from Elsevier and Julie Brown, MD, MPH.Citation17
Figure 5 Proposed child restraint options for the administration of an epinephrine auto-injector.