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Diabetes, Metabolic Syndrome and Obesity Volume 11, 2018 - Issue
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Depression in people with type 2 diabetes: current perspectives

Lina Darwish1 Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada, [email protected];2 Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada, [email protected];3 Cardiac Rehabilitation Program, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada, [email protected];4 Canadian Partnership for Stroke Recovery, Toronto, ON, Canada, [email protected]
,
Erika Beroncal1 Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada, [email protected];2 Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada, [email protected];3 Cardiac Rehabilitation Program, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada, [email protected]
,
Ma Veronica Sison1 Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada, [email protected];2 Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada, [email protected];3 Cardiac Rehabilitation Program, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada, [email protected]
&
Walter Swardfager1 Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada, [email protected];2 Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada, [email protected];3 Cardiac Rehabilitation Program, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada, [email protected];4 Canadian Partnership for Stroke Recovery, Toronto, ON, Canada, [email protected]Correspondence[email protected]
Pages 333-343 | Published online: 10 Jul 2018

Figures & data

Figure 1 Venn diagram exploring intersections between symptoms of MDD (teal), diabetes-related distress (blue), fatigue (orange), and anhedonia (green).

Notes: Items are derived from the DDS-17Citation133 and Diagnostic And Statistical Manual Of Mental Disorders-5 diagnostic criteria for a depressive episode.Citation5 Both diabetes-related distress and depression can share symptoms of fatigueCitation41,Citation46,Citation47 and/or anhedonia (including anticipatory, motivational, decisional, and consummatory dimensions).
Abbreviations: DDS, Diabetes Distress Scale; MDD, major depressive disorder.
Figure 1 Venn diagram exploring intersections between symptoms of MDD (teal), diabetes-related distress (blue), fatigue (orange), and anhedonia (green).

Figure 2 Temporal trend in depressive symptoms with duration of diabetes.

Notes: Results from separate studies reporting trends in depressive symptoms (colored lines) suggest a J-shaped curve (dashed line). Initial and later peaks are observed, which are thought to result from different biopsychosocial factors (colored shaded bars). The high prevalence of MDD (18%–25%) contributes to the overall prevalence of depressive symptoms, but temporal trends with duration of diabetes have not been described explicitly.
Abbreviation: MDD, major depressive disorder.
Figure 2 Temporal trend in depressive symptoms with duration of diabetes.

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