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ORIGINAL RESEARCH

Difference in Gastrointestinal Risk Associated with Use of GLP-1 Receptor Agonists: A Real-World Pharmacovigilance Study

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Pages 155-163 | Published online: 13 Jan 2022

Figures & data

Table 1 Characteristics of Patients Who Suffered Gastrointestinal Adverse Drug Reactions When Using Semaglutide or Liraglutide

Table 2 RORs for Gastrointestinal Adverse Drug Reactions Upon Use of Semaglutide or Liraglutide

Figure 1 Differences in reporting of gastrointestinal adverse drug reactions between different GLP-1RAs as a radar chart. (A) Reporting-risk profile. (B) Time-to-onset profile. RORs (95% CIs) for reporting risk were calculated through a logarithmic transformation.

Figure 1 Differences in reporting of gastrointestinal adverse drug reactions between different GLP-1RAs as a radar chart. (A) Reporting-risk profile. (B) Time-to-onset profile. RORs (95% CIs) for reporting risk were calculated through a logarithmic transformation.

Table 3 Time-to-Onset of Cases with Semaglutide- or Liraglutide-Associated Gastrointestinal Adverse Drug Reactions

Figure 2 Reporting risk for gastrointestinal adverse drug reactions with GLP-1RAs grouped by subcutaneous dose. (A) Semaglutide. (B) Liraglutide. RORs (95% CIs) were calculated through a logarithmic transformation.

Abbreviations: ROR, reporting odds ratio; CI, confidence interval.
Figure 2 Reporting risk for gastrointestinal adverse drug reactions with GLP-1RAs grouped by subcutaneous dose. (A) Semaglutide. (B) Liraglutide. RORs (95% CIs) were calculated through a logarithmic transformation.