Neck Circumference is Associated with Metabolic Syndrome Components in Chinese Subjects with Type 2 Diabetes

Figures & data

Table 1 Correlation of Neck Circumference with Anthropometric Parameters

	Neck Circumference
	Males (n=312)		Females (n=298)		All (n=610)
	r	P	r	P	r	P
BMI	0.575	<0.001	0.661	<0.001	0.530	<0.001
WC	0.464	<0.001	0.604	<0.001	0.489	<0.001
WHR	0.380	<0.001	0.368	<0.001	0.373	<0.001

Abbreviations: r, Pearson’s correlation coefficient; BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio.

Table 2 Correlation of Neck Circumference with Metabolic Variables

	Neck Circumference
	Males (n=312)		Females (n=298)		All (n=610)
	r	P	r	P	r	P
SBP	0.119	0.035	0.165	0.004	0.111	0.006
DBP	0.161	0.004	0.220	<0.001	0.185	<0.001
TG	0.178	0.002	0.131	0.024	0.120	0.003
TC	0.036	0.531	0.011	0.853	−0.033	0.410
HDL-C	−0.125	0.027	−0.14	0.015	−0.18	<0.001
LDL-C	0.031	0.589	0.002	0.979	−0.02	0.616
HbA1c	−0.005	0.927	−0.074	0.191	−0.043	0.284
UA	0.177	0.002	0.261	<0.001	0.240	<0.001

Abbreviations: r, Pearson’s correlation coefficient; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; TC, total cholesterol; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; UA, uric acid.

Table 3 Comparison of NC Between MetS Group and Non-MetS Group

	MetS (n=397)	Non-MetS (n=213)	P value
Male NC (cm)	38.42±3.05	36.20±2.90	<0.001
Female NC (cm)	36.14±2.75	34.01±2.94	<0.001
All subjects NC (cm)	37.29±3.16	35.15±3.11	<0.001

Abbreviations: NC, neck circumference; MetS, metabolic syndrome.

Figure 1 Receiver operating characteristic (ROC) curves of neck circumference for identifying metabolic syndrome in Males and Females. The areas under the ROC curves (AUCs) were calculated to evaluate the predictive values of NC for MetS. The AUCs of NC were 0.701 (95% confidence interval [CI], 0.643–0.760) for males and 0.707 (95% CI, 0.641–0.773) for females. Youden index was calculated and NC ≥ 37.3 cm (sensitivity 0.662, specificity 0.649) for males and NC ≥ 35.8 cm (sensitivity 0.59, specificity 0.67) for females was considered as the best cutoff values in identifying MetS.

Table 4 Identification Rate of MetS Components by NC and WC*

	Males			Females
	NC	WC	P value	NC	WC	P value
High SBP	59.43%	54.29%	0.331	55.90%	74.87%	0.000
High DBP	65.63%	60.42%	0.455	55.84%	76.62%	0.006
Hypertriglyceridemia	71.74%	77.17%	0.398	60.00%	80.95%	0.002
Low HDL-C	59.86%	57.82%	0.722	54.17%	69.44%	0.059
Hyperuricemia	63.16%	76.32%	0.212	66.04%	79%	0.127

Note: *Using NC cut-off point (male≥37.3cm, female≥35.8cm) and WC cut-off point (male≥90cm, female≥85cm) to recognize disorders.

Abbreviations: High SBP, SBP≥130mmHg; High DBP, DBP≥85mmHg; Hypertriglyceridemia, TG≥ 1.7mmol/L; Low HDL-C, HDL-C<1.04mmol/L; Hyperuricemia, uric acid≥420nmol/L in males and≥ 360 nmol/L in females.