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ORIGINAL RESEARCH

Association of Non-Insulin-Based Insulin Resistance Indices with Risk of Incident Prediabetes and Diabetes in a Chinese Rural Population: A 12-Year Prospective Study

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Pages 3809-3819 | Received 11 Aug 2022, Accepted 06 Dec 2022, Published online: 12 Dec 2022

Figures & data

Figure 1 Flowchart of participant selection for the study cohort.

Abbreviations: FBG, fasting blood glucose; IFG, impaired fasting glucose; T2DM, type 2 diabetes mellitus.
Figure 1 Flowchart of participant selection for the study cohort.

Table 1 Characteristics of Participants According to Fasting Glycemia Levels at Baseline (n=2209)

Table 2 Association of Three IR Indices with T2DM or IFG at Baseline Using Logistic Regression Analysis (n=2209)

Table 3 Cox Proportional Hazards Regression Analysis of Risk of Incident IFG by Tertile of Baseline TyG Index, TG/HDL-C Ratio and METS-IR (n=1205)

Table 4 Cox Proportional Hazards Regression Analysis of Risk of Incident T2DM by Tertile of Baseline TyG Index, TG/HDL-C Ratio and METS-IR (n=1205)

Figure 2 Linear relationship of the TyG index with risk of incident diabetes (p for linear=0.011). The model was adjusted for age, sex, educational status, cigarette smoking, drinking, physical activity, family history of hypertension and diabetes, BMI, WC, FBGSBP, TC, TG, LDL and HDL-C.

Abbreviations: T2DM, type 2 diabetes mellitus; TyG, triglyceride glucose; CI, confidence interval; BMI, body mass index; WC, waist circumference; FBG, fasting blood glucose; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; LDL and HDL-C, low- and high-density lipoprotein cholesterol.
Figure 2 Linear relationship of the TyG index with risk of incident diabetes (p for linear=0.011). The model was adjusted for age, sex, educational status, cigarette smoking, drinking, physical activity, family history of hypertension and diabetes, BMI, WC, FBGSBP, TC, TG, LDL and HDL-C.