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ORIGINAL RESEARCH

Where to Initiate Basal Insulin Therapy: Inpatient or Outpatient Department? Real-World Observation in China

, ORCID Icon, , &
Pages 3375-3385 | Received 15 Aug 2022, Accepted 18 Oct 2022, Published online: 31 Oct 2022

Figures & data

Figure 1 Flow of patients included in the analysis. Patients ever admitted to hospital or lost to follow-up after insulin therapy initiation during 6-month study period were excluded.

Figure 1 Flow of patients included in the analysis. Patients ever admitted to hospital or lost to follow-up after insulin therapy initiation during 6-month study period were excluded.

Table 1 Baseline Characteristics of Inpatients and Outpatients Initiated with Basal Insulin

Figure 2 Evolution of insulin therapy after 6-month follow-up for inpatient and outpatient initiation. (A) Treatment transition after 6 months among all patients. (B) Treatment transition after 6 months among patients initiated with basal insulin alone. (C) Treatment transition after 6 months among patients initiated with basal-bolus insulin.

Figure 2 Evolution of insulin therapy after 6-month follow-up for inpatient and outpatient initiation. (A) Treatment transition after 6 months among all patients. (B) Treatment transition after 6 months among patients initiated with basal insulin alone. (C) Treatment transition after 6 months among patients initiated with basal-bolus insulin.

Figure 3 Proportion achieving HbA1c <7% between patients persistent or nonpersistent to initial insulin therapy after 6 months.

Note: 60 patients were not included in the analysis due to no results after 6 months. *Odds ratios were adjusted for region, patient resource (inpatient or outpatient initiation), age, gender, education, residence, hospital levels, disease duration, BMI, initiation with basal only or basal-bolus insulin and baseline HbA1c levels.
Figure 3 Proportion achieving HbA1c <7% between patients persistent or nonpersistent to initial insulin therapy after 6 months.

Table 2 Subgroup Analysis of Proportion Achieving HbA1c <7% Among Persistent and Nonpersistent Groups Between Inpatient Initiators and Outpatient Initiators After 6 Months

Table 3 Comparison of Proportion Achieving HbA1c <7% After 6 Months Between Inpatient and Outpatient Insulin Initiation by HOC Level Among Patients Persisting with Initial Insulin Therapy