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ORIGINAL RESEARCH

Patient-Reported Outcomes Following the Use of Jiang Tang San Huang Tablets in Type 2 Diabetes Mellitus: A Retrospective Cohort Study in a Chinese Population

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Pages 4023-4033 | Received 13 Sep 2022, Accepted 08 Dec 2022, Published online: 23 Dec 2022

Figures & data

Table 1 Composition of the Jiang Tang San Huang Tablet

Table 2 Questionnaire Items for the Treatment of T2DM with JTSH Tablet

Figure 1 Flowchart of this study.

Abbreviations: T2DM, type 2 diabetes mellitus; JTSH tablets, Jiang Tang San Huang tablets.
Figure 1 Flowchart of this study.

Table 3 The Distribution of Clinical Conditions of JTSH Tablet Users

Figure 2 Representations of the results of the questionnaire items. (A) Satisfaction of 147 patients’ with JTSH tablets treatment for T2DM. (B) The hypoglycemic regimens administered to the enrolled patients. (C) Evaluation of the advantages of JTSH tablets for treating of T2DM by lowering blood sugar or improving symptoms in 147 patients. (D) A total of 147 patients evaluated the disadvantages of JTSH tablets for the treatment of T2DM. (E) Evaluation of the hypoglycemic effect of antidiabetic drugs in 147 patients. (F) Evaluation of diet and exercise done well or not of 147 patients.

Abbreviations: JTSH tablets, Jiang Tang San Huang tablets; T2DM, type 2 diabetes mellitus.
Figure 2 Representations of the results of the questionnaire items. (A) Satisfaction of 147 patients’ with JTSH tablets treatment for T2DM. (B) The hypoglycemic regimens administered to the enrolled patients. (C) Evaluation of the advantages of JTSH tablets for treating of T2DM by lowering blood sugar or improving symptoms in 147 patients. (D) A total of 147 patients evaluated the disadvantages of JTSH tablets for the treatment of T2DM. (E) Evaluation of the hypoglycemic effect of antidiabetic drugs in 147 patients. (F) Evaluation of diet and exercise done well or not of 147 patients.

Figure 3 Hypoglycemic effect and islet protection effect of Jiang Tang San Huang tablets (JTSH tablets) in the treatment of type 2 diabetes mellitus. (A) Changes in glycosylated haemoglobin levels before and after treatment with JTSH tablet in 68 patients. (B) Changes in 2-hour postprandial blood glucose levels before and after treatment with JTSH tablets in 57 patients. (C) Changes in glycosylated haemoglobin levels before and after treatment with JTSH tablet in 43 patients. (D) Changes in HOMA-IR levels before and after treatment with JTSH tablet in 37 patients. (E) Changes in HOMA-β levels before and after treatment with JTSH tablet in 43 patients.

Notes: P-values are calculated comparing post-treatment with JTSH tablets and the baseline values. *P < 0.05; **P < 0.01; ***P < 0.001.
Abbreviations: 2HPG, 2-hour postprandial blood glucose; FPG, fasting plasma glucose; HbA1c, glycated haemoglobin; HOMA-IR, homeostasis model assessment of the insulin resistance index; HOMA-β, homeostasis model assessment of β-cell function.
Figure 3 Hypoglycemic effect and islet protection effect of Jiang Tang San Huang tablets (JTSH tablets) in the treatment of type 2 diabetes mellitus. (A) Changes in glycosylated haemoglobin levels before and after treatment with JTSH tablet in 68 patients. (B) Changes in 2-hour postprandial blood glucose levels before and after treatment with JTSH tablets in 57 patients. (C) Changes in glycosylated haemoglobin levels before and after treatment with JTSH tablet in 43 patients. (D) Changes in HOMA-IR levels before and after treatment with JTSH tablet in 37 patients. (E) Changes in HOMA-β levels before and after treatment with JTSH tablet in 43 patients.

Table 4 Logistic Regression Between JTSH Tablet Administration and Glycaemic Control