Cerebral Modifications in Glaucoma and Macular Degeneration: Analysis of Current Evidence in Literature and Their Implications on Therapeutic Perspectives

Figures & data

Table 1 Demographic and Clinical Characteristics

N. Patients						Mean Age (in Yrs.)
AMD		JMD		CONTROLS		AMD		JMD		CONTROLS
174		190		325		74.1^°		39.3^°		47.6^°°
POAG	NTG		PACG		CONTROLS	POAG	NTG		PACG		CONTROLS
1192	156		154		1178	54*	53.9**		49.9***		50.3****

Notes: °Value subject to approximation - out of a total of studies 26 did not provide the average age but only the range; 1 did not provide data about age. Two studies shared the same patients; °°Value subject to approximation - out of a total of 19 studies 2 did not provide the average age but only the range; 1 did not provide data about age; *Value subject to approximation - out of a total of 45 studies 2 gave the average age of a group consisting of POAG and NTG without distinction between the two subgroups; 2 gave the average age of a group consisting of POAG and PACG without distinction between the two subgroups; 1 did not give the average age but only the range; **Value subject to approximation - out of a total of 8 studies, 2 gave the average age of a group consisting of POAG and NTG without distinction between the two subgroups; 1 did not give the average age but only the range; ***Value subject to approximation - out of a total of 7 studies 2 gave the average age of a group consisting of POAG and PACG without distinction between the two subgroups; ****Value subject to approximation - out of a total of 52 studies 1 did not provide the average age but only the range; 3 did not provide a given age.

Figure 1 (A) Brodmann area 17, lateral and medial view. (B) Brodmann area 18, lateral and medial view. (C) Brodmann area 19, lateral and medial view. Notes: Adapted from: Brodmann K. Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues [Comparative localization theory of the cerebral cortex presented in its principles on the basis of the cell structure]. Leipzig: Johann Ambrosius Barth Verlag; 1909. German.¹²⁹

Figure 2 Calcarine fissure (in red), medial view. Gray H. Anatomy of the Human Body. Philadelphia: Lea & Febiger; 1918.¹³⁰

Figure 3 (A) Brodmann area 7, lateral and medial view. (B) Brodmann area 46, lateral and medial view. Brodmann K. Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues [Comparative localization theory of the cerebral cortex presented in its principles on the basis of the cell structure]. Leipzig: Johann Ambrosius Barth Verlag; 1909. German.¹²⁹

Brodmann K. Vergleichende Lokalisationslehre der Grosshirnrinde in ihren Prinzipien dargestellt auf Grund des Zellenbaues [Comparative localization theory of the cerebral cortex presented in its principles on the basis of the cell structure]. Leipzig: Johann Ambrosius Barth Verlag; 1909. German.

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Gray H. Anatomy of the Human Body. Philadelphia: Lea & Febiger; 1983.

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