Anti-VEGF therapy in the management of retinopathy of prematurity: what we learn from representative animal models of oxygen-induced retinopathy

Figures & data

Figure 1 Models of rat (A) and mouse (B) OIR and retinal flat mounts stained with lectin to visualize the vasculature.

Notes: *avascular retinal area; white arrow points to area with intravitreal neovascularization. Reprinted from Ophthalmology, Volume 122, Hartnett ME. Pathophysiology and mechanisms of severe retinopathy of prematurity, Pages 200–210, Copyright 2015, with permission from Elsevier.⁴⁵
Abbreviations: OIR, oxygen-induced retinopathy; p, postnatal day.

HartnettMEPathophysiology and mechanisms of severe retinopathy of prematurityOphthalmology201512220021025444347

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