Diagnostic accuracy of HIV test kits, Genscreen Ultra and Bioelisa

Figures & data

Table 1 Panels used for validation

Country/organization of origin	HIV negative	HIV positive	HIV-1	HIV-2	HIV dual
Ethiopia	80	50	50
Cameroon	7	15	15
Cote d’Ivoire	45	30	16	4	10
Kenya	45	30	30
South Africa	3	15	15
Thailand	20	15	15
Uganda		7	7
SeraCare		32	32
BBI (Boston Biomedical Inc.)		6		6
Total	200	200	180	10	10

Table 2 Reference and Genscreen ULTRA HIV Ag–Ab test result

Test kit	Reference standard positive	Reference standard negative
Genscreen ULTRA HIV Ag–Ab Positive	199	3
Genscreen ULTRA HIV Ag–Ab Negative	1	197
	200	200

Table 3 Test accuracy of Genscreen ULTRA HIV Ag–Ab

Indicators	Estimate (%)	95% CI
Sensitivity	99.5	97.2–99.9
Specificity	98.5	95.7–99.7
Positive predictive value	98.5	95.7–99.7
Negative predictive value	99.5	97.2–99.9

Table 4 Reference and Bioelisa HIV-1 +2 Ag/Ab test results

Test kit	Reference standard positive	Reference standard negative
Bioelisa HIV-1 +2 Ag/Ab positive	198	3
Bioelisa HIV-1 +2 Ag/Ab negative	2	197
	200	200

Table 5 Test accuracy of Bioelisa HIV-1 +2 Ag/Ab

Indicator	Estimate (%)	95% CI
Sensitivity	99	96.4–99.7
Specificity	98.5	95.7–99.7
Positive predictive value	98.5	95.7–99.7
Negative predictive value	99	96.4–99.7