Virological Outcomes Among Pregnant Women Receiving Antiretroviral Treatment in the Amhara Region, North West Ethiopia

Figures & data

Table 1 Demographic and Clinical Characteristics of Pregnant Women Attending ART Clinics for ART Follow-Up in Amhara Region, 2021/2022

Variables		Number	%
Age	12–22	79	8.0%
	23–33	694	70.0%
	34–45	216	21.8%
	≥46	3	0.3%
Breastfeeding	No	936	94%
	Yes	56	6%
WHO Stage	I	902	90.9%
	II	65	6.6%
	III	17	1.7%
	IV	8	0.8%
Adherence	Good >95%	974	98%
	Fair (85–94%)	13	1%
	Poor <85%	5	1%
Test reason	Routine Viral load testers	956	96%
	Suspected Viral load testers	36	4%
Regimen Type	First Line	983	99.1%
	Second Line	9	0.9%
Combination Type	EFV Based	124	12.5%
	NVP Based	630	63.5%
	PI Based	217	21.9%
	NRTIs	21	2.1%

Table 2 Non-Suppression Rate Difference Between Different Categories of Pregnant Women Attending ART Clinics for ART Follow-Up in Amhara Region, 2021/2022

Variables		Suppressed (n)	Non-Suppressed (n)	Suppression Rate (%)	P value
Regimen Type	First-line	895	88	91%	0.168
	Second-line	7	2	77.8%
Age	12–22	73	6	92%	0.409
	23–33	628	66	90%
	34–45	199	17	92%
	≥46	2	1	67%
Breastfeeding	No	852	84	91%	0.399
	Yes	50	6	89%
Stage	I	824	78	91%	0.006
	II	60	5	92%
	III	13	4	76%
	IV	5	3	63%
Adherence	Good >95%	891	83	91%	0.000
	Fair (85–94%)	11	7	61%
Reason	Routine Viral load	881	75	92%	0.000
	Suspected Viral load	21	15	58%
Treatment category	EFV Based	116	8	93.5%	0.649
	NVP Based	568	62	90.2%
	PI Based	199	18	91.7%
	NRTIs	19	2	90.5%

Table 3 Risk Factors Associated with Viral Non-Suppression Among Pregnant Women Attending ART Clinics for ART Follow-Up in Amhara Region, 2021/2022

Variables		Suppression Status		Crude OD Ratio (95% CI)	Adjusted OD Ratio (95% CI)	P value
		Suppressed (N)	Non-Suppressed (N)
Age	12–22	73	6	1	-
	23–33	628	66	1.3 (0.536–3.053)	-	0.580
	34–45	199	17	1.03 (0.395–2.738)	-	0.938
	≥46	2	1	6.1 (0.479–77.187)	-	0.164
Breastfeeding	No	852	84	1	-
	Yes	50	6	1.2 (0.507–2.923)	-	0.660
WHO Stage	I	824	78	1	1
	II	60	5	0.9 (0.343–2.257)	0.8 (0.309–2.228)	0.712
	III	13	4	3.3 (1.035–10.209)	3.4 (1.045–11.048)	0.042
	IV	5	3	6.4 (1.487–27.023)	6.0 (1.317–27.512)	0.021
Adherence	Good >95%	891	83	1	1
	Fair (85–94%)	9	4	6.8 (2.579–18.092)	5.1 (1.667–15.719)	0.000
Test reason	Routine Viral load	881	75	1	1
	Suspected Viral load	21	15	8.4 (4.153–16.952)	6.7 (3.147–14.089)	0.000
Treatment category	EFV Based	116	8	1	1
	NVP Based	568	62	1.58 (0.738–3.394)	-	0.238
	PI Based	199	18	1.31 (0.553–3.111)	-	0.538
	NRTIs	19	2	1.53 (0.301–7.741)	-	0.610