First molecular characterization of related cases of healthcare-associated infections involving multidrug-resistant Enterococcus faecium vanA in Algeria

Figures & data

Figure 1 Timeline of patients with VREfm and isolate characteristics.

Notes: V, vancomycin treatment (for other antimicrobials, refer text). ^†Death of the patient. *Enterococcus faecium vanA isolation (from peritoneal pus in patients 1 and 4, blood culture in patient 2, and postsurgical wound in patient 3). **ASP and genotype defined in the text.
Abbreviations: ASP, antimicrobial susceptibility pattern; F, female; M, male; MLST, multilocus sequence typing; MR-PCR, multiplex rep-PCR; PFGE, pulsed-field gel electrophoresis; rep-PCR, repetitive sequence-based polymerase chain reaction; ST, sequence type; VREfm, vancomycin-resistant Enterococcus faecium; w, week.

Figure 2 (A) Minimum spanning tree generated using the goeBURST algorithm implemented in the PHYLOViZ software showing the position of the four studied strains (black) among the whole population of VanA-type strains (n=1,064) deposited in the Enterococcus faecium PubMLST database⁴⁹ on September 5, 2016. Each circle corresponds to an ST. The number given in the circle corresponds to the ST designation. The size of each circle is proportional to the number of isolates of each ST. Red indicates strains of human origin, dark green indicates strains of animal origin, light green indicates strains of environmental origin, and gray indicates strains with no associated information on their origin. (B) Focus on cluster including strains of ST80. (C) Focus on cluster including the ST789 isolate.

Abbreviation: ST, sequence type.

Enterococcus faecium MLST Databases [homepage on the Internet]. Website sited at the University of Oxford (Jolley & Maiden 2010, BMC Bioinformatics, 11:595) [updated July 16, 2018]. Available from: https://pubmlst.org/efaecium. Accessed July 3, 2018.

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