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Original Research

The impact of initial antibiotic treatment failure: real-world insights in patients with complicated, health care-associated intra-abdominal infection

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Pages 329-343 | Published online: 31 Jan 2019

Figures & data

Table 1 Patient demographic and clinical characteristics at index hospitalization, overall and by country

Table 2 Summary of procedures performed during hospitalization for the index infection

Figure 1 Most common bacterial pathogens identified in specimen samples from patients in Brazil (A), France (B), Italy (C), Russia (D), Spain (E) and overall (F).

Notes: Patients could have more than one pathogen type identified. Data missing for 22 patients in Brazil. Percentages are calculated as a proportion of those patients with ≥1 bacterial pathogen identified.

Figure 1 Most common bacterial pathogens identified in specimen samples from patients in Brazil (A), France (B), Italy (C), Russia (D), Spain (E) and overall (F).Notes: Patients could have more than one pathogen type identified. Data missing for 22 patients in Brazil. Percentages are calculated as a proportion of those patients with ≥1 bacterial pathogen identified.

Table 3 Characteristics of IAT overall and by country

Table 4 Treatment outcome measures, overall and by country

Figure 2 Clinical outcomes of initial antibiotic therapy in patients receiving (A) monotherapy or (B) combination therapy.

Figure 2 Clinical outcomes of initial antibiotic therapy in patients receiving (A) monotherapy or (B) combination therapy.

Figure 3 Initial antibiotic therapy failure in patients (A) with and (B) without multi-drug-resistant pathogens identified.

Figure 3 Initial antibiotic therapy failure in patients (A) with and (B) without multi-drug-resistant pathogens identified.

Table 5 Statistical predictors of initial antibiotic treatment failure – univariate and multivariate analyses

Table S1 IECs and IRBs consulted

Table S2 Bacterial pathogens identified in specimen samples, including multidrug-resistant organisms, overall and by country