Figures & data
Figure 1 (A) Neutrophile gating by CD45/SS. (B) MFI of nCD64 for an isotype control (M1), normal neonate (M2), and septic neonate (M3).
Abbreviations: FITC, fluorescein isothiocyanate; MFI, mean fluorescence intensity; PerCP: peridinin chlorophyll protein complex.
Table 1 General, clinical, and laboratory data of studied neonates
Figure 2 (A) Blood culture results among septic neonates. (B) Microorganisms identified in blood culture of septic neonates.
Table 2 Levels of CRP, presepsin, nCD64, and sTREM-1 in studied groups
Table 3 Cut-off values, sensitivities, and specificities for early detection of neonatal sepsis as calculated on ROC curves for studied biomarkers
Figure 3 (A) ROC curve for CRP, prespsin, sTREM-1, nCD64, separately and in combination (prespsin, sTREM-1, and nCD64). (B) ROC curve for combined CRP and nCD64, CRP and sTREM-1, and CRP, sTREM-1, and nCD64.
Abbreviations: ROC, receiver operating characteristic; nCD64, neutrophil CD64; sTREM-1, soluble triggering receptor expressed on myeloid cells-1.
Table 4 Correlations between CRP, sTREM-1, and nCD64
Table S1 General and clinico-laboratory data of EOS and LOS neonates under study
Table S2 Levels of CRP, presepsin, nCD64, and sTREM-1 in EOS and LOS studied group
Table S3 Levels of CRP, presepsin, nCD64, and sTREM-1 in proven sepsis and probable sepsis groups