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Review

Acinetobacter baumannii Efflux Pumps and Antibiotic Resistance

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Pages 423-434 | Published online: 12 Feb 2020

Figures & data

Figure 1 Five main MDEPs with their well-known examples and antibiotic substrates. Data from Yılmaz and Özcengiz.Citation91

Abbreviations: OMP, outer membrane protein; SMR, the small multidrug resistance family; MFS, the major facilitator superfamily; ABC, ATP-binding cassette superfamily; MATE, the multidrug and toxic compound extrusion family; RND, the resistance-nodulation division family.

Figure 1 Five main MDEPs with their well-known examples and antibiotic substrates. Data from Yılmaz and Özcengiz.Citation91Abbreviations: OMP, outer membrane protein; SMR, the small multidrug resistance family; MFS, the major facilitator superfamily; ABC, ATP-binding cassette superfamily; MATE, the multidrug and toxic compound extrusion family; RND, the resistance-nodulation division family.

Figure 2 Schematic organization of the ade gene cluster. Data from Wieczorek et al.Citation13

Figure 2 Schematic organization of the ade gene cluster. Data from Wieczorek et al.Citation13

Table 1 Efflux Pump Families in Acinetobacter baumannii with Strains Which Pumps Described for the First Time

Figure 3 Structures of the main developed Efflux pump inhibitors.

Figure 3 Structures of the main developed Efflux pump inhibitors.