https://orcid.org/0000-0002-2901-2801
Figures & data
Table 1 Antibiotic Susceptibilities of Strain EcHK001 and the E. coli J53 Transconjugants
Figure 1 S1-PFGE and Southern blotting. Lane M, marker (Salmonella H9812); Lane 1, E. hormaechei EcHK001; Lane 2, the transconjugants; Lane 3, Southern blotting of EcHK001 with the probes specific to blaNDM-1. The black arrows indicate the plasmid pNDM-EcHK001.
Figure 2 Phylogenetic tree of E. hormaechei strain EcHK001 with other 19 available E. cloacae complex genomes from GenBank. Strain EcHK001 is marked with a solid triangle. Isolates from China are indicated with red shading.
Figure 3 The genetic map of plasmid pNDM-EcHK001. GC content, GC skew+ and GC skew- are, respectively, indicated in black, green and purple. The MDR regions are indicated in red. The modules of conjugal transfer, plasmid replication and plasmid stability are, respectively, indicated in orange, pink and blue. The other elements are indicated in grey.
Table 2 pNDM-EcHK001-Like Plasmids Harboring blaNDM Among Enterobacterales
Figure 4 The genetic structure features of pNDM-EcHK001-like plasmids. The blaNDM-1 and blaSHV-12 gene are indicated in red and yellow. The blaNDM variants and the blaSHV-11 gene are indicated in purple and dark orange. The insertion sequences ΔISAba125, IS5 and IS26 are indicated in black. Other genes in ΔTn125 and blaSHV-12-carrying transposon are indicated in light gray and dark gray, respectively.
