Figures & data
Table 1 Summary of Chloroquine Phosphate Tablet Samples Collected and Physicochemical Results
Table 2 Summary of Quinine Sulphate Tablet Samples Collected and Physicochemical Results
Table 3 System Suitability Test Results for Chromatographic Method of Assay of Chloroquine Phosphate and Quinine Sulphate Tablets
Table 4 Packaging and Labeling Information of Samples of Chloroquine Phosphate and Quinine Sulphate Tablets
Figure 1 Chromatograph Peak Retention Times of (A) Chloroquine Phosphate USP Standard Reference (B) Chloroquine Phosphate Sample, in a reserved phase column, RP-18, 150 × 4.6 mm; 5μm packing when 22% (v/v) methanol and 78% (v/v) phosphate buffer solution adjusted to pH of 2.5 used as mobile phase, at flow rate of 1.2 mL/minute; the detection wavelength 224 nm, injection volume 10 µL, and temperature of 25°C. (C) Quinine Sulfate USP Standard Reference (D) Quinine Sulfate Sample in a reserved phase column RP-18, 150 × 43.9 mm; 5μm packing when mixture of water, acetonitrile, methanesulfonic acid solution and diethylamine solution in the ratio of 86:10:2:2 to pH of 2.6 used as a mobile phase, and flow rate 1.0 mL/minute, the detection wavelength 235 nm, injection volume 50 µL, and temperature of 25°C on Agilent 1260 HPLC.
