Analysis of Urinary Pathogen Cultures and Drug Sensitivity in Patients with Urinary Stones for Five Consecutive Years in Xiangya Hospital, China

Figures & data

Table 1 Top 10 Most Frequently Detected Pathogens in Urine Cultures from Patients with Urinary Calculi

Pathogens	Pathogens Number	Total Proportion	Proportion of GN/GP Bacillus
Escherichia coli	149	53.6%	71.3%^a
Enterococcus faecalis	25	9.0%	36.2%^b
Klebsiella pneumoniae	22	7.9%	10.5%^a
Monilia albicans	15	5.4%	21.7%^b
Enterococcus faecium	14	5.0%	20.3%^b
Pseudomonas aeruginosa	14	5.0%	6.7%^a
Proteus mirabilis	13	4.7%	6.2%^a
Enterobacter cloacae	11	4.0%	5.3%^a
Candida glabrata	9	3.2%	13.1%^b
Staphylococcus epidermidis	6	2.2%	8.7%^b

Abbreviations: ^aGN, Gram-negative; ^bGP, Gram-positive.

Figure 1 Distribution of pathogens over the 5-year period from 2014 to 2018 (A, B).

Figure 2 Detection rates of Gram-negative bacilli (A) and Gram-positive cocci (B) over the 5-year period.

Figure 3 The total number of pathogens detected over the 5-year period.

Table 2 Sensitivity of the Major Gram-Negative E. Coli Isolates to Commonly Used Antibacterial Drugs (%)

Escherichia coli
Antibacterial Drugs	2014		2015		2016		2017		2018
	S	I	S	I	S	I	S	I	S	I
Ampicillin Trihydrate	16	9	21	3	0	4	18	0	10	0
Ampicillin/Sulbactam	36	13	36	8	17	13	36	7	30	20
Cefazolin	42	0	41	0	43	0	29	4	40	10
Ceftriaxone	44	0	38	0	48	0	29	0	50	0
Cefoperazone/Sulbactam	93	0	95	0	83	4	93	4	100	0
Ceftazidime	69	2	79	3	74	0	71	0	70	0
Cefepime	98	0	92	0	70	0	71	0	90	0
Aztreonam	58	0	38	31	48	0	50	4	70	0
Imipenem	91	2	97	0	91	0	96	0	100	0
Gentamicin	67	2	59	0	100	0	64	0	70	10
Amikacin	98	0	95	0	96	0	100	0	100	0
Levofloxacin	40	4	46	0	26	0	29	7	70	0
Ciprofloxacin	38	0	41	0	22	4	32	0	60	0
Bactrim	56	0	56	0	57	0	46	0	80	0
Nitrofurantoin	84	4	92	3	78	9	89	7	100	0

Abbreviations: S, susceptible I, intermediate.

Table 3 Sensitivity of the Major Gram-Positive E. Faecalis Isolates to Commonly Used Antibacterial Drugs (%)

Antibacterial Drugs	Enterococcus faecalis
	2014		2015		2016		2017		2018
	S	I	S	I	S	I	S	I	S	I
Ampicillin Trihydrate	50	0	63	0	75	0	40	0	100	0
Ampicillin/Sulbactam	33	0	75	0	100	0	80	0	100	0
Penicillin	83	0	88	0	75	0	40	0	80	0
Gentamicin	67	2	75	0	75	0	80	0	80	0
Levofloxacin	40	4	100	0	75	0	40	0	80	0
Nitrofurantoin	100	0	88	0	100	0	40	20	100	0
Tetracycline	50	0	50	0	0	0	20	0	60	20
Erythrocin	67	0	38	0	13	25	20	0	60	0
Ciprofloxacin	100	0	100	0	50	13	40	0	80	0
Chloramphenicol	100	0	100	0	100	0	100	0	100	0
Clindamycin	83	0	50	0	0	0	20	0	60	0
Moxifloxacin	100	0	100	0	50	13	40	0	80	0

Abbreviations: S, susceptible; I, intermediate.