The Performance of the Abbott Real Time MTB RIF/INH Compared to the MTBDRplus V2 for the Identification of MDR-TB Among Isolates

Anura David1 Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence[email protected]

https://orcid.org/0000-0003-1590-198X

Lyndel Singh1 Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South Africa

Pedro Da Silva1 Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South Africa;2 National Priority Program, National Health Laboratory Services, Johannesburg, South Africa

https://orcid.org/0000-0002-9869-5271

Lesley Scott1 Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South Africa

https://orcid.org/0000-0001-6573-9525

Wendy Stevens1 Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg, South Africa;2 National Priority Program, National Health Laboratory Services, Johannesburg, South Africa

The Performance of the Abbott Real Time MTB RIF/INH Compared to the MTBDRplus V2 for the Identification of MDR-TB Among Isolates

Table 1 Rif and INH Resistance Profile Determined by the SOC MTBDRplus V2 and the RT MTB RIF/INH

Table 2 Summary of Mutations Reported by the GenoType ^® MTBDRplus V2 Assay

Table 3 Summary of Mutations Reported by the Abbott RT MTBRIF/INH Assay

Table 4 List of Discrepant Results and Validation with Sequencing

Table 5 Summary of High-Throughput Rif and INH Genotyping Technologies

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The Performance of the Abbott Real Time MTB RIF/INH Compared to the MTBDRplus V2 for the Identification of MDR-TB Among Isolates

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Table 1 Rif and INH Resistance Profile Determined by the SOC MTBDRplus V2 and the RT MTB RIF/INH

Table 2 Summary of Mutations Reported by the GenoType ® MTBDRplus V2 Assay

Table 3 Summary of Mutations Reported by the Abbott RT MTBRIF/INH Assay

Table 4 List of Discrepant Results and Validation with Sequencing

Table 5 Summary of High-Throughput Rif and INH Genotyping Technologies

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Table 2 Summary of Mutations Reported by the GenoType ^® MTBDRplus V2 Assay