Intraoperative Cefuroxime Irrigation Prophylaxis for Acute-Onset Endophthalmitis After Phacoemulsification Surgery

Figures & data

Table 1 Characteristics of the 11 Eyes Suffering Endophthalmitis in Group 1

	Age (Y)	Sex	Eye	Postoperative Presentation (Days)	CDVA at Presentation (LogMAR)	Procedure	Final CDVA (LogMAR)	Final Outcome
1	71	F	Right	1	0.92	TA+SA+AI+IVAI	0.30	Improved
2	56	F	Left	1	0.82	TA+SA+AI+IVAI	0.22	Improved
3	54	F	Right	1	1.0	TA+SA+AI	0.52	Improved
4	75	M	Left	1	0.30	TA+SA+AI	0.30	Unchanged
5	37	F	Left	1	1.70	TA+SA+AI+IVAI+ PPV, IVAI for twice	1.30	Improved
6	57	F	Right	1	2.0	TA+SA+AI+ IVAI+ PPV	0.52	Improved
7	77	F	Right	20	0.22	TA+SA+AI	0.10	Improved
8	63	F	Right	2	3.0	TA+SA+AI+IVAI+PPV, IVAI for three times	1.70	Improved
9	73	F	Left	21	0.40	TA+SA+AI	0.22	Improved
10	77	F	Right	16	0.40	TA+SA+AI+IVAI, IVAI for twice	0.22	Improved
11	79	F	Right	1	1.0	TA+SA+AI+ IVAI+ PPV	0.30	Improved

Abbreviations: CDVA, corrected distance visual acuity; TA, topical antibiotics; SA, systemic antibiotics; AI, antibiotic irrigation; IVAI, intravitreal antibiotic injection; PPV, pars plana vitrectomy.

Table 2 Characteristics of the 5 Eyes Suffering Endophthalmitis in Group 2

	Age (Y)	Sex	Eye	Postoperative Presentation (Days)	CDVA at Presentation (LogMAR)	Procedure	Final CDVA (LogMAR)	Final Outcome
1	61	M	Right	4	0.60	TA+SA+AI+ IVAI	0	Improved
2	60	M	Left	19	1.40	TA+SA+AI+IVAI+ PPV, IVAI for twice	1.52	Regressive
3	73	F	Left	1	0.22	TA+SA+AI	0.15	Improved
4	74	F	Right	1	0.40	TA+SA+AI	0.10	Improved
5	67	F	Left	30	0.22	TA+AI+ IVAI	0.15	Improved

Abbreviations: CDVA, corrected distance visual acuity; TA, topical antibiotics; SA, systemic antibiotics; AI, antibiotic irrigation; IVAI, intravitreal antibiotic injection; PPV, pars plana vitrectomy.

Table 3 Causative Microorganisms and Their Antibiotic Susceptibility Patterns in the Five Cases with Endophthalmitis

Group	Causative Microorganisms	Antibiotic Susceptibility	Antibiotic Resistance
Group 1	Staphylococcus hominis subsp	Vancomycin, cefuroxime, tobramycin	Gentamycin
	Neisseria mucosa	Vancomycin, tobramycin, cefuroxime, gatifloxacin	Cefazolin
	Corynebacterium xerosis	Vancomycin, tobramycin, cefuroxime, gatifloxacin	Cefazolin, cefaclor
	Enterococcus faecalis	Vancomycin, gatifloxacin, tetracycline	Cefuroxime
Group 2	Streptococcus gordonii	Vancomycin, ceftazidime, cefuroxime, gatifloxacin	Tobramycin, gentamycin