Molecular Characteristics of Carbapenem-Resistant Enterobacter cloacae in a Tertiary Hospital in China

Figures & data

Table 1 Clinical Characteristics of Carbapenem-Resistant Enterobacter cloacae Strains

Isolate Number	Isolation Date	Age	Gender	Sample	Ward
1	2016.11	71	M	Blood	ICU
2	2018.9	85	M	Sputum	ICU
3	2018.11	70	M	Sputum	General surgery
4	2019.1	71	M	Sputum	ICU
5	2019.1	60	M	Blood	ICU
6	2019.2	61	M	Sputum	ICU
7	2019.2	63	M	Blood	ICU
8	2019.3	67	F	Blood	ICU
9	2019.6	66	M	Wound	Orthopaedics
10	2019.6	47	M	Wound	Pain management
11	2019.6	75	F	Sputum	ICU
12	2019.7	55	M	Wound	Pain management

Table 2 Molecular Characteristics and Antimicrobial Susceptibilities of Carbapenem-Resistant Enterobacter cloacae Strains

Isolate Number	Carbap-Enemase	CTX_M	Ampc	ST	MEM	IPM	ATM	FEP	CAZ	CTX	TZP	SAM	GEN	AMK	CIP	LVX	COL	SXT	TCY	CHL
1	NDM-1	-	-	171	8	4	>16	>16	>16	>32	>64	>16	>8	≤8	>2	>8	≤0.5	>2	>8	>16
2	NDM-1	CTX-M-3	DHA1	78	8	>8	16	>16	>16	>32	>64	>16	≤2	≤8	>2	>8	≤0.5	>2	8	16
3	IMP-26	-	-	544	>8	4	≤2	>16	>16	>32	32	>16	>8	≤8	>2	>8	≤0.5	>2	>8	16
4	IMP-26	-	-	544	>8	4	≤2	>16	>16	>32	≤4	>16	>8	≤8	>2	8	≤0.5	>2	>8	>16
5	IMP-26	-	-	544	8	4	≤2	>16	>16	>32	≤4	>16	>8	≤8	>2	8	≤0.5	>2	>8	>16
6	KPC-2	CTX-M-3	-	78	>8	8	>16	>16	>16	>32	>64	>16	≤2	≤8	>2	>8	≤0.5	>2	8	16
7	IMP-26	-	-	544	8	8	≤2	>16	>16	>32	16	>16	>8	≤8	>2	>8	≤0.5	>2	>8	>16
8	IMP-26	-	-	544	8	4	≤2	>16	>16	>32	8	>16	≤2	≤8	>2	>8	≤0.5	>2	>8	>16
9	NDM-5	-	-	114	>8	>8	>16	>16	>16	>32	>64	>16	>8	≤8	>2	>8	≤0.5	>2	>8	>16
10	NDM-5	-	-	97	>8	>8	≤2	>16	>16	>32	>64	>16	>8	≤8	>2	>8	≤0.5	>2	>8	>16
11	IMP-26	-	-	544	>8	>8	≤2	>16	>16	>32	≤4	>16	>8	≤8	>2	>8	≤0.5	>2	>8	>16
12	NDM-5			114	>8	>8	>16	>16	>16	>32	>64	>16	>8	≤8	2	2	≤0.5	2	8	>16

Abbreviations: MEM, meropenem; IPM, imipenem; ATM, aztreonam; FEP, cefepime; CAZ, ceftazidime; CTX, cefotaxime; TZP, piperacillin/tazobactam; SAM, ampicillin/sulbactam; AMK, amikacin; CIP, ciprofloxacin; LVX, levofloxacin; COL, colistin; GEN, gentamicin; SXT, trimethoprim/sulfamethoxazole; TCY, tetracycline; CHL, chloramphenicol.

Figure 1 Multi-locus sequence typing (MLST) phylogenetic tree of the 12 carbapenem-resistant E. cloacae strains.

Figure 2 Dendrogram of patterns for carbapenem-resistant Enterobacter cloacae isolates obtained by PFGE.