Analysis of Salmonella typhimurium Protein-Targeting in the Nucleus of Host Cells and the Implications in Colon Cancer: An in-silico Approach

Figures & data

Figure 1 Computational prediction of nuclear targeting of S. typhimurium proteins in host cells and their relationship with various parameters.

Figure 2 Computational prediction of total targeting of S. typhimurium proteins in host cells and their relationship with various parameters.

Table 1 Details of Possible Protein Targeting in Different Subcellular Locations of the Host Cell by BaCeILo and Hum-mPLoc 2.0, Using the Complete Salmonella typhimurium Proteome

Protein Targeting in Different Subcellular Locations	Number of Proteins Predicted by BaCeILo	Number of Proteins Predicted by Hum-mPLoc 2.0
Nucleus	331	867
Mitochondria	921	654
Cytoplasm	2069	707
Secretory/Plasma membrane	1397	–
Plasma Membrane	–	289
Endoplasmic reticulum	–	215
Golgi apparatus	–	15
Peroxisome	–	64
Microsome	–	01
Lysosome	–	18
Extracellular	–	444
Centrosome	–	01
Cytoskeleton	–	0
Multiple location	–	1360
Unknown	–	83