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Case Report

Fatal Prosthetic Valve Endocarditis Due to Aspergillus flavus in a Diabetic Patient

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Pages 2245-2250 | Published online: 10 Jul 2020

Figures & data

Figure 1 (A) Fluoroscopy of mechanical prosthetic mitral valve showed one fixed leaflet. (B) Mechanical prosthetic mitral valve from surgery showed large thrombus and pannus. (C) Chest X-ray demonstrated pulmonary edema.

Figure 1 (A) Fluoroscopy of mechanical prosthetic mitral valve showed one fixed leaflet. (B) Mechanical prosthetic mitral valve from surgery showed large thrombus and pannus. (C) Chest X-ray demonstrated pulmonary edema.

Figure 2 (A, B) Transesophageal echocardiography showed large vegetation (arrow) of aorta.

Figure 2 (A, B) Transesophageal echocardiography showed large vegetation (arrow) of aorta.

Figure 3 (A) Dichotomous branching hyphae in KOH preparation (magnification 40×). (B) Dichotomous branching hyphae in PAS stain (magnification 40×). (C) The microscopic appearance of Aspergillus flavus, showing an echinulate colorless conidiophore and a globose vesicle covered by uniseriate phialides with globose echinulate conidia.

Figure 3 (A) Dichotomous branching hyphae in KOH preparation (magnification 40×). (B) Dichotomous branching hyphae in PAS stain (magnification 40×). (C) The microscopic appearance of Aspergillus flavus, showing an echinulate colorless conidiophore and a globose vesicle covered by uniseriate phialides with globose echinulate conidia.

Figure 4 Agarose-gel electrophoresis of ß-tubulin PCR products. Lane N, negative control; lane A, DNA extracted from negative blood culture; lane B DNA extracted from colonies grown on SDA; lane M, 100,bp DNA size marker.

Figure 4 Agarose-gel electrophoresis of ß-tubulin PCR products. Lane N, negative control; lane A, DNA extracted from negative blood culture; lane B DNA extracted from colonies grown on SDA; lane M, 100,bp DNA size marker.