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Original Research

Therapeutic Drug Monitoring and Nephrotoxicity of Teicoplanin Therapy in Chinese Children: A Retrospective Study

, , , , , , , , & show all
Pages 4105-4113 | Published online: 12 Nov 2020

Figures & data

Table 1 Patients’ Characteristics

Figure 1 Distribution of teicoplanin trough concentrations. Panel (A) shows the distribution of Cmin on day 3 or day 4 after teicoplanin administration. Panel (B) shows the distribution of teicoplanin Cmin at steady state.

Figure 1 Distribution of teicoplanin trough concentrations. Panel (A) shows the distribution of Cmin on day 3 or day 4 after teicoplanin administration. Panel (B) shows the distribution of teicoplanin Cmin at steady state.

Table 2 Univariate and Multivariate Analyses of the Variables Tested for Potential Association with C3/4min/DCLD

Table 3 Univariate and Multivariate Analyses of the Variables Tested for Potential Association with CSSmin/DMD

Table 4 Univariable and Multivariable Analysis of Risk Factors for Nephrotoxicity in Patients Receiving Teicoplanin

Figure 2 Classification and regression tree model for the nephrotoxicity of teicoplanin therapy. A value of 0 indicated that no nephrotoxicity was observed and a value of 1 indicated that nephrotoxicity was observed.

Figure 2 Classification and regression tree model for the nephrotoxicity of teicoplanin therapy. A value of 0 indicated that no nephrotoxicity was observed and a value of 1 indicated that nephrotoxicity was observed.