Heterogeneity of Helicobacter pylori Strains Isolated from Patients with Gastric Disorders in Guiyang, China

Mengheng Mi1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China

Fangcao Wu1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China

Jian Zhu3 Department of Gastroenterology, Guiyang Hospital of Guizhou Aviation Industry Group, Guiyang, People’s Republic of China

Fang Liu1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China

Guzhen Cui1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;4 Key Laboratory of Endemic and Ethnic Diseases (Guizhou Medical University), Ministry of Education, Guiyang, People’s Republic of China

Xueqing Wen1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China

Yue Hu5 Department of Gastroenterology, Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China

Zhaohui Deng3 Department of Gastroenterology, Guiyang Hospital of Guizhou Aviation Industry Group, Guiyang, People’s Republic of China

Xiaojuan Wu1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China

Zhengrong Zhang1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;4 Key Laboratory of Endemic and Ethnic Diseases (Guizhou Medical University), Ministry of Education, Guiyang, People’s Republic of China

Tingna Qi1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;4 Key Laboratory of Endemic and Ethnic Diseases (Guizhou Medical University), Ministry of Education, Guiyang, People’s Republic of China

Zhenghong Chen1 Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, School of Basic Medical Science, Guizhou Medical University/Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China;2 Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of ChinaCorrespondence[email protected]

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Figures & data

Table 1 Primer Sequences and PCR Conditions

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Table 2 Antibiotic Breakpoints

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Table 3 Antibiotic Susceptibility and Typing of 65 Monoclonal Strains Isolated from 13 Patients

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Figure 1 Electropherogram of RAPD-PCR typing of Helicobacter pylori strains from 13 patients.

Notes: M: 2K DNA ladder; G1–G13: sample/patient number; bands 1–5: monoclonal strains from a single patient amplified using primer 1247; and bands 6–10: monoclonal strains from a single patient amplified using primer 1283.

Heterogeneity of Helicobacter pylori Strains Isolated from Patients with Gastric Disorders in Guiyang, China

Table 1 Primer Sequences and PCR Conditions

Table 2 Antibiotic Breakpoints

Table 3 Antibiotic Susceptibility and Typing of 65 Monoclonal Strains Isolated from 13 Patients

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Heterogeneity of Helicobacter pylori Strains Isolated from Patients with Gastric Disorders in Guiyang, China

Figures & data

Table 1 Primer Sequences and PCR Conditions

Table 2 Antibiotic Breakpoints

Table 3 Antibiotic Susceptibility and Typing of 65 Monoclonal Strains Isolated from 13 Patients

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