Viral Etiologies of Meningitis in Patients with Presumed Pyogenic Meningitis at University Hospitals in Ethiopia

Figures & data

Table 1 Bivariate Correlation of Demographic and Clinical Variables with PCR Positivity for HEVs at AHRI, 2019

Variables		HEVs		p-value	COR	95% C.I.
		Positive (%)	Negative (%)
Age	0–19 yrs.	10 (19.6)	41 (80.4)	0.049	8.29	1.01, 68.1
	19+ yrs.	1 (2.9)	34 (97.1)		1
Sex	Male	8 (15.7)	43 (84.3)	0.34	0.5	0.12, 2.05
	Female	3 (8.3)	32 (91.7)		1
Fever	Yes	8 (13.3)	52 (86.7)	0.82	0.85	0.21, 3.49
	No	3 (11.5)	23 (88.5)		1
Impaired consciousness	Yes	7 (14.6)	41 (85.4)	0.58	1.45	0.39, 5.38
	No	4 (10.5)	34 (89.5)		1
Vomiting	Yes	8 (13.3)	52 (86.7)	0.82	0.85	0.21, 3.49
	No	3 (11.5)	23 (88.5)		1
Stiffness	Yes	5 (9.4)	48 (90.6)	0.25	2.1	0.6, 7.65
	No	6 (18.2)	27 (81.8)		1
Seizure	Yes	6 (17.6)	28 (82.4)	0.28	0.5	0.14, 1.78
	No	5 (9.6)	47 (80.4)		1
CSF appearance	Clear	5 (17.2)	24 (82.8)	0.38	0.57	0.16, 2.04
	Turbid	6 (10.5)	51 (89.5)		1

Abbreviations: yrs., years; Fever, temperature ≥ 38 o c; COR, crude odds ratio; CI, confidence interval.

Table 2 PCR Findings with Specific Etiologic Agents in Patients Presumptively Diagnosed Pyogenic Meningitis at AHRI, 2019

PCR Finding	Bacteria Identified			Total
	No	N. meningitidis	S. pneumoniae
Negative	47	0	0	47
Positive for bacteria	0	18	10	28
Positive for Enteroviruses*	7	0	0	7
Positive for bacteria + Enteroviruses*	0	3	1	4
Total	54	21	11	86

Note: *CMV was negative in all assayed samples.