Acute Infectious Endophthalmitis After Cataract Surgery: Epidemiological Characteristics, Risk Factors and Incidence Trends, 2008–2019

Figures & data

Figure 1 Annual distribution of endophthalmitis after cataract surgery.

Figure 2 Trend chart of cataract surgery volume and incidence of postoperative infectious endophthalmitis in our hospital in recent 12 years.

Table 1 Univariate Analysis of Patients with Endophthalmitis After Cataract Surgery

	Number of Endophthalmitis/Number of Cataract Surgery	Incidence Rate	P value*
Year
2008–2011	18/7651	0.24%	0.000
2012–2015	15/13,409	0.11%
2016–2019	9/34,552	0.026%
Gender
Male	15/22,679	0.066%	0.532
Female	27/32,933	0.081%
Age (years)
≤44	3/1561	0.192%	0.067
45–59	8/7891	0.101%
60–74	24/28,013	0.085%
≥75	7/18,147	0.038%
Diabetes
Y	8/10,306	0.078%	0.845
N	34/45,306	0.075%
Rupture of posterior capsule
Y	2/371	0.539%	0.032
N	40/55,241	0.072%
Antibiotic
Y	4/28,171	0.014%	0.000
N	38/27,441	0.138%
Behind-the-lens washout
Y	9/34,552	0.026%	0.000
N	33/21,060	0.157%

Notes: *Chi-square test was used for the factors of operation year and age, and Fisher test was used for sex, diabetes, rupture of posterior capsule, antibiotics and behind-the-lens washout factors.

Abbreviations: Y, yes; N, no.

Table 2 Multivariate Logistic Regression Analysis of Endophthalmitis After Cataract Surgery

Factors	OR	95% C.I.	P value*
Rupture of posterior capsule	3.861	0.922–16.162	0.064
Age	0.696	0.487–0.997	0.048
Year	0.521	0.318–0.853	0.010
Antibiotics	0.316	0.100–1.004	0.051

Note: *Multivariate logistic regression analysis used for the factors of rupture of posterior capsule, age, year and antibiotics.

Figure 3 Clinical manifestations of endophthalmitis: a report of 42 cases.

Table 3 Results of Laboratory Bacterial Cultures of 42 Cases Intraocular Specimens of Endophthalmitis

Species	No.	%
Negative	17	63.0
Coagulase-negative Staphylococci	1	3.7
Staphylococcus aureus	2	7.4
Enterococci	1	3.7
Pseudomonas species	1	3.7
Streptococcus	2	7.4
Other gram-positive bacteria	2	7.4
Other gram-negative bacteria	1	3.7
Total	27	100