139
Views
4
CrossRef citations to date
0
Altmetric
Case Report

Fecal Microbiota Transplantation as an Effective Treatment for Carbapenem-Resistant Klebsiella pneumoniae Infection in a Renal Transplant Patient

, ORCID Icon, , , , , & show all
Pages 1805-1811 | Published online: 14 May 2021

Figures & data

Figure 1 Treatment timeline for CRKP infection.

Figure 1 Treatment timeline for CRKP infection.

Figure 2 Surgical incision and renal function indexes in the patient post-FMT. (A) Surgical incision for kidney transplantation in the patient. (B) Serum creatinine and blood urea nitrogen (BUN) levels.

Figure 2 Surgical incision and renal function indexes in the patient post-FMT. (A) Surgical incision for kidney transplantation in the patient. (B) Serum creatinine and blood urea nitrogen (BUN) levels.

Figure 3 Alpha and beta diversity of the gut microbiota of the donor and the patient pre- and post-FMT. Histograms compared Chao1 index (A) and Shannon index (B) of the fecal microbiome in the donor and the patient pre- and post-FMT. PCoA plots showed the microbial community variation of the donor and the patient pre- and post-FMT based on weighted UniFrac distance (C) and unweighted UniFrac distance (D). FMT 1W, FMT 3W and FMT 2M represented 1 week, 3 weeks and 2 months after FMT.

Abbreviations: D, donor; R, recipient.
Figure 3 Alpha and beta diversity of the gut microbiota of the donor and the patient pre- and post-FMT. Histograms compared Chao1 index (A) and Shannon index (B) of the fecal microbiome in the donor and the patient pre- and post-FMT. PCoA plots showed the microbial community variation of the donor and the patient pre- and post-FMT based on weighted UniFrac distance (C) and unweighted UniFrac distance (D). FMT 1W, FMT 3W and FMT 2M represented 1 week, 3 weeks and 2 months after FMT.

Figure 4 Gut microbial compositions of the donor and the patient pre- and post-FMT. (A) Cumulative histograms representing average distributions of major taxa at genus level. FMT 1W, FMT 3W and FMT 2M represented 1 week, 3 weeks and 2 months after FMT. (B) Pie chart representing the relative abundance of Klebsiella (red). (C) Network diagrams showing the relationship between Klebsiella and other genera. Red indicated positive correlation and blue indicated negative correlation.

Abbreviations: D, donor; R, recipient.
Figure 4 Gut microbial compositions of the donor and the patient pre- and post-FMT. (A) Cumulative histograms representing average distributions of major taxa at genus level. FMT 1W, FMT 3W and FMT 2M represented 1 week, 3 weeks and 2 months after FMT. (B) Pie chart representing the relative abundance of Klebsiella (red). (C) Network diagrams showing the relationship between Klebsiella and other genera. Red indicated positive correlation and blue indicated negative correlation.