Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan

Figures & data

Table 1 Demographic Characteristics, Previous Infection with SARS CoV-2 and Type of Vaccine Received by the Participants (N=400)

Characteristics	Frequency (n and %)
Sex
Male	325 (81.3)
Female	75 (18.8)
Age (Mean±SD)	39.6±12.04
Age groups
≤ 40 years	227 (56.8)
> 40 years	173 (43.3)
Employment
Doctor	122 (30.5)
Administration officer	173 (43.3)
Support staff	105 (26.3)
Previous infection with SARS CoV-2
Yes	238 (59.5)
No	162 (40.5)
Type of COVID-19 vaccine
ChAdOx1 nCoV-19 vaccine (AstraZeneca)	400 (100)

Figure 1 Adverse reactions reported by the participants after receiving the first dose of the COVID-19 vaccine (in percentage).

Table 2 Adverse Reactions Reported by the Participants and Their Association with Participants’ Ages

	Frequency (n and %)
	Age ≤ 40 Years	Age > 40 Years	Chi-Square
	(n=227)	(n=173)	p value
Adverse reactions (any)	214 (94.3)	160 (92.5)	0.472
Headache	111 (48.9)	75 (43.4)	0.271
Fatigue	157 (69.2)	108 (62.4)	0.158
Chills and shiver	120 (52.9)	81 (46.8)	0.231
Diarrhea	27 (11.9)	20 (11.6)	0.918
Fever	160 (70.5)	105 (60.7)	0.04
Joint pain	110 (48.5)	77 (44.5)	0.433
Muscle pain	167 (73.6)	106 (61.3)	0.009
Nausea	28 (12.3)	24 (13.9)	0.650
Sore throat	61 (26.9)	46 (26.6)	0.950
Local pain	136 (59.9)	99 (57.2)	0.589
Local swelling	37 (16.3)	24 (13.9)	0.504

Table 3 Adverse Reactions Reported by the Participants and Their Association with Previous SARS CoV-2 Infection

	Frequency (n and %)
	Previous Infection with SARS CoV-2
	Yes	No	Chi-Square
	(n=238)	(n=162)	p value
Adverse reactions (any)	229 (96.2)	145 (89.5)	0.008
Headache	112 (47.1)	74 (45.7)	0.786
Fatigue	168 (70.6)	97 (59.9)	0.026
Chills and shiver	123 (51.7)	78 (48.1)	0.488
Diarrhea	29 (12.2)	18 (11.1)	0.743
Fever	166 (69.7)	99 (61.1)	0.073
Joint pain	113 (47.5)	74 (45.7)	0.723
Muscle pain	167 (70.2)	106 (65.4)	0.318
Nausea	33 (13.9)	19 (11.7)	0.533
Sore throat	70 (29.4)	37 (22.8)	0.145
Local pain	143 (60.1)	92 (56.8)	0.511
Local swelling	36 (15.1)	25 (15.4)	0.933