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ORIGINAL RESEARCH

Evaluation of Wound Healing and Antibacterial Activities of Solvent Fractions of 80% Methanol Leaf Extract of Brucea antidysenterica J.F. Mill (Simaroubaceae)

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, &
Pages 1517-1531 | Published online: 05 Apr 2022

Figures & data

Figure 1 Picture of Brucea antidysenterica (photograph taken by principal investigator during sample collection).

Figure 1 Picture of Brucea antidysenterica (photograph taken by principal investigator during sample collection).

Table 1 Formula Used to Formulate Simple Ointment and Medicated Ointment

Figure 2 Excision wounding of animals. 3A- circularly marked area to be excised, 3B - excised wound area.

Figure 2 Excision wounding of animals. 3A- circularly marked area to be excised, 3B - excised wound area.

Figure 3 Incision wound experiment. Showing a 3cm longitudinal wound created on dorsal area of animals, sutured 1cm apart and the continuous water flow experiment to investigate breaking strength of wound site.

Figure 3 Incision wound experiment. Showing a 3cm longitudinal wound created on dorsal area of animals, sutured 1cm apart and the continuous water flow experiment to investigate breaking strength of wound site.

Table 2 The Effect of Solvent Fractions of 80% Methanol Extract of B. antidysenterica Leaves on Wound Contraction of Excision Wound in Rat

Table 3 The Effect of Solvent Fractions of 80% Methanol Extract of B. Antidysenterica Leaves on Epithelialization Period of Excision Wound in Rats

Figure 4 Pictograph of wound contraction of animal treated with aqueous fraction of 80% methanol extract of B. antidysenterica leaf on different days of measurement.

Figure 4 Pictograph of wound contraction of animal treated with aqueous fraction of 80% methanol extract of B. antidysenterica leaf on different days of measurement.

Table 4 The Effect of Solvent Fractions of 80% Methanol Extract of B. antidysenterica Leaves on the Breaking Strength of the Incision Wound Site in Rats

Table 5 The Mean Bacterial Growth Inhibition Zone (mm) of Solvent Fractions of 80% Methanol Extract of B. antidysenterica Leaves in Agar Well Diffusion Method (20µL Sample Volume)

Table 6 The MIC (mg/mL) and MBC (mg/mL) of Solvent Fractions of 80% Methanol Extract of B. antidysenterica Leaves Using Tube Dilution Method

Table 7 Phytochemical Screening of Solvent Fractions of 80% Methanol Extract of B. antidysenterica Leaves