Ten-Year Analysis of Pathogenic Factors and Etiological Characteristics of Endophthalmitis from a Tertiary Eye Center in North China

Qing Liu1 Qingdao Eye Hospital of Shandong First Medical University, Qingdao, People’s Republic of China;2 State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, People’s Republic of ChinaView further author information

Lei Wan1 Qingdao Eye Hospital of Shandong First Medical University, Qingdao, People’s Republic of China;2 State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, People’s Republic of ChinaView further author information

Jinyan Zhou1 Qingdao Eye Hospital of Shandong First Medical University, Qingdao, People’s Republic of China;2 State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, People’s Republic of ChinaView further author information

Yusen Huang1 Qingdao Eye Hospital of Shandong First Medical University, Qingdao, People’s Republic of China;2 State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Eye Institute of Shandong First Medical University, Qingdao, People’s Republic of ChinaCorrespondence[email protected]
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Table 1 Predisposing Factors of 524 Patients by Endophthalmitis Etiology

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Table 2 Distribution of Pathogens Isolated from Endophthalmitis Patients by Clinical Setting

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Table 3 Overall Susceptibility Rate of Isolated Gram-Positive and Gram-Negative Bacteria to Different Antibiotics

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Figure 1 Time trend of overall antibiotic susceptibility rate from 2011 to 2020 in Qingdao Eye Hospital. Some antibiotics were omitted as the numbers of isolates that underwent susceptibility testing were not comparable between periods. The overall susceptibility rate for Ceftazidime decreased significantly from 81.58% in 2011–2015 to 60.87% in 2016–2018 (P<0.05). Similarly, Tobramycin decreased from 72.36% to 59.37% (P<0.05) and Gentamicin from 69.56% to 55.00% (P<0.05).

Note: *P<0.05.

Figure 2 Time trends of bacterial susceptibilities. 1, 2010 to 2012; 2, 2013 to 2014; 3, 2015 to 2016; 4, 2017 to 2018; 5, 2019 to 2020.

Table 4 Susceptibility Rate of Isolated Fungus to Different Antibiotics in Fungal Endophthalmitis

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Ten-Year Analysis of Pathogenic Factors and Etiological Characteristics of Endophthalmitis from a Tertiary Eye Center in North China

Table 1 Predisposing Factors of 524 Patients by Endophthalmitis Etiology

Table 2 Distribution of Pathogens Isolated from Endophthalmitis Patients by Clinical Setting

Table 3 Overall Susceptibility Rate of Isolated Gram-Positive and Gram-Negative Bacteria to Different Antibiotics

Table 4 Susceptibility Rate of Isolated Fungus to Different Antibiotics in Fungal Endophthalmitis

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Ten-Year Analysis of Pathogenic Factors and Etiological Characteristics of Endophthalmitis from a Tertiary Eye Center in North China

Figures & data

Table 1 Predisposing Factors of 524 Patients by Endophthalmitis Etiology

Table 2 Distribution of Pathogens Isolated from Endophthalmitis Patients by Clinical Setting

Table 3 Overall Susceptibility Rate of Isolated Gram-Positive and Gram-Negative Bacteria to Different Antibiotics

Table 4 Susceptibility Rate of Isolated Fungus to Different Antibiotics in Fungal Endophthalmitis

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