Prevalence of Tuberculosis and the Determinants of Lose to Follow-Up the Treatment for Tuberculosis Patients in Case of Buno Bedele and Ilu Ababor Zones, Oromia, Ethiopia

Figures & data

Table 1 Demographic Characteristics of Categorical Covariate

Covariate	Categories	Number(%) of Participants	Number(%) of Loss to Follow-Up	Number(%) of Censored	Median	(Max, Min)
Sex	Male	189(50.4%)	48(25.4%)	141(74.6%)	220	[187.097, 252.903]
	Female	186(49.6%)	45(24.2%)	141(75.8%)	198	[193.173, 202.827]
Phase of TB treatment	Intensive phase	168 (44.8%)	42(25%)	126(75%)	199	[179.138, 218.862]
	Continuation Phase	207(55.2%)	51(24.6%)	156(75.4%)	198	[174.385, 221.615]
TB type	SPTB	141(37.6%)	38(27%)	103(73%)	212.867	[200.300, 225.433]
	SNTB	108(28.8%)	27(25%)	81(75%)	202.388	[183.708, 221.067]
	ETB	126(33.6%)	28(22.2%)	98(77.8%)	216.904	[201.898, 231.909]
TB category	New	301(80.3%)	76(25.2%)	225(74.8%)	212.239	[201.526, 222.952]
	Relapse	57(15.2%)	15(26.3%)	42(73.7%)	221.500	[219.421, 223.579]
	Failure	9(2.4%)	1(11.1%)	8(88.9%)	207.775	[192.158, 223.391]
	Defaulter	8(2.1%)	1(12.5%)	7(87.5%)	229.326	[215.546, 243.107]
Previous TB history	No	203 (54.1%)	49 (31.8%)	154(68.2%)	168	[158, 168]
	Yes	172 (45.9%)	44(25.6%)	128(74.4%)	220	[200.790, 239.210]
HIV co-infection	Yes	20(5.3%)	86(24.2%)	269(75.8%)	201.607	[190.394, 212.820]
	No	355(94.7)	7(35%)	13(65%)	168	[162.878, 173.122]
Co-morbidity	No	160(42.7%)	41(25.6%)	119(74.4%)	198	[180.909, 215.091]
	Yes	215(57.3%)	52(24.2%)	163(75.8%)	220	[188.132, 251.868]
DM	Yes	333(88.8%)	9(21.4%)	33(78.6%)	216.381	[201.086, 231.677]
	No	42(11.2%)	84(25.2%)	249(74.8%)	219.282	[206.354, 232.209]
Cancer	Yes	357(95.2%)	7(38.9%)	11(61.1%)	220	[202.25, 237.745]
	No	18(4.8%)	86(24.1%)	271(75.9%)	198	[195.639, 200.361]
Anemia	Yes	340(90.7%)	12(34.3%)	23(65.7%)	219.975	[204.397, 235.553]
	No	35(9.3%)	81(23.8%)	259(76.2%)	209.427	[195.069, 223.785]
Physical inactive	Yes	4(1.1%)	2(50%)	2(50%)	168	[49.739, 286.261]
	No	371(98.9%)	91(24.5%)	280(75.5%)	199	[182.127, 215.873]
Total		375	93(24.8%)	282(75.2%)	199	[182.144, 215.856]

Figure 1 The Kaplan–Meier survival curve of the overall TB patients’ treatment.

Figure 2 The Kaplan–Meier survival curve of the TB patients regarding phase of TB.

Table 2 Comparison of Survival Experience of TB Patients

Covariates	df	Log Rank Test
		Chi-Square	P-value
Sex	1	0.27	0.6034
Marital status	3	16.56	0.0009
Phase of TB treatment	1	0.27	0.6051
TB type	2	2.32	0.3141
TB category	3	1.01	0.7991
Previous TB status	1	0.13	0.7170
Co-morbidity	1	0.11	0.7414
HIV co infection	1	5.38	0.0204
Diabetes mellitus	1	19.42	0.0000
Cancer	1	6.13	0.0133
Anemia	1	17.87	0.0000
Physical inactive	1	0.25	0.6176

Table 3 Univariable Cox PH Analysis

Covariates	P-value
Sex	0.648
Age	0.053
Marital status	0.572
Phase of TB treatment	0.000
TB type	0.359
TB category	0.462
Previous TB status	0.750
Co-morbidity	0.772
HIV co infection	0.038
Diabetes mellitus	0.000
Cancer	0.035
Anemia	0.000
Physical inactive	0.638

Table 4 Multivariable Cox PH Analysis

Covariates	Haz. Ratio	Std. Err.	Z	P>z	[95% Conf. Interval]
Age	0.9896617	0.0033516	−3.07	0.002	0.9831144	0.9962526
1.Phase of TB treatment	1.088068	0.1161647	0.79	0.429	0.8826323	1.34132
1.HIV/TB Co-infection	1.756786	0.4096811	2.42	0.016	1.112293	2.774715
1.DM	1.40302	0.3145673	1.51	0.131	0.9041041	2.177256
1.Cancer	0.7838992	0.2104713	−0.91	0.365	0.4631469	1.326789
1.Anaemia	1.789683	0.4528684	2.30	0.021	1.089895	2.938783
Cons	0.0000665	0.0000225	−28.40	0.000	0.0000342	0.0001291

Table 5 Test of Proportional-Hazards Assumption

Time	Chi-Square	df	Prob>chi2
Global test	5.68	6	0.4596