Lactoferrin versus Long-Acting Penicillin in Reducing Elevated Anti-Streptolysin O Titer in Cases of Tonsillopharyngitis

Figures & data

Table 1 Demographic Data of All Studied Patients

Variable	Group	Frequency	P value
Group frequency	Lactoferrin	39
	Penicillin	39
	Penicillin plus lactoferrin	39
Age	Lactoferrin	8.4 ±2.7	0.08
	Penicillin	7.8 ±2.4
	Penicillin plus lactoferrin	9 ±1.6
Male sex	Lactoferrin	19 (48.7%)	0.9
	Penicillin	21 (53.8%)
	Penicillin plus lactoferrin	20 (51.3%)
Female sex	Lactoferrin	20 (51.3%)
	Penicillin	18 (46.2%)
	Penicillin plus lactoferrin	19 (48.7%)

Table 2 Comparision Between Serum Level of ASOT Pre and Three Months Post Treatment and Six Months Post Treatment in the Three Studied Groups

Variable	Lactoferrin (1)	Long Acting Penicillin (2)	Lactoferrin +Penicillin (3)	P value (1&2)	P value (1&3)	P value (2&3)	P value Krauskal wills
Pre-treatment ASOT (median±range)	610±2955	720±2420	700±2510	0.3	0.2	0.9	0.3
Post- treatment ASOT 3 months (median±range)	370±440	420±560	350±450	0.02*	0.4	0.004*	0.008*
Post- treatment ASOT 6 months (median±range)	350±420	420±550	340±440	0.02*	0.5	0.007*	0.01*

Note: *Means significant.

Table 3 Percentage of Change in ASOT After Three Months and Six Months of Treatment in the Three Studied Groups

	ASOT Pre- (1)	ASOT Post-3 (2)	ASOT Post-6 (3)	Change After 3ms	Change After 6ms	Change From 3 to 6 ms.	P value 1 and 2	P value 1 and 3	P value 2 and 3
Lactoferrin	610±2955	370± 440	350± 420	54% decrease	55% decrease	2% decrease	0.000*	0.000*	0.000*
Penicillin	720±2420	420± 560	420± 550	51% decrease	51% decrease	No change	0.000*	0.000*	0.1
Penicillin plus lactoferrin	700±2510	350± 450	340± 440	59% decrease	60% decrease	1.6% decrease	0.000*	0.000*	0.000*

Note: *Means significant.