Infection of Severe Fever with Thrombocytopenia Syndrome Virus as a Cause of a Child’s Fever of Unknown Origin: A Case Report

Figures & data

Table 1 Changes of Infection and Immunological Indexes in the Child with SFTS

Date	WBC (×10^9/L)	PLT (×10^9/L)	CRP (mg/L)	PCT (ng/mL)	FIB (g/L)	IL-1β (pg/mL)	IL-2R (U/mL)	IL-6 (pg/m)	IL-8 (pg/m)	IL-10 (pg/mL)	TNF-α (pg/mL)
July 5th	1.91	78	0.5
July 6th	1.4	47	0.2	3.16	2.02	5.46	1096	3.33	14.0	127	11.3
July 9th	10.61	86	2.5	0.75	3.18	22.6	1120	<2	7.41	18.6	15.8
July 13th	4.4	271	8.8		6.11	6.51	706	<2	15.2	<5	14.6
Reference value	3.5–9.5	125–350	0–3	0–0.046	2–4	0–5	223–710	0–5.9	0–62	0–9.1	0–8.1

Table 2 Demographic and Epidemiological Characteristics of the 10 Cases of SFTS in Children from China, from 2011 to 2022

Variables		Total
		N	%
Gender	Male	4	40
	Female	6	60
Risk condition	Contact with SFTS cases	3	30
	Resting and playing in grassland	7	70
	A history of tick bites	3	30
	A history of mosquito bites	2	20

Table 3 Clinical and Laboratory Characteristics of the 10 Cases of SFTS in Children from China, from 2011 to 2022

Variables		Total
		N	%
Signs and symptoms	Fever	10	100
	Weakness	10	100
	Dyspnea	0	0
	Cough	0	0
	Headache	2	20
	Abdominal pain	0	0
	Nausea	4	40
	Dizziness	2	20
	Myalgia	0	0
	Arthralgia	1	10
	Swollen lymph nodes	3	30
	Hematuria	1	10
	Proteinuria	3	30
	Skin eruption	3	30
	Disturbance of consciousness	0	0
	Sinus tachycardia	2	20
	Thrombocytopenia (<60 × 10^9/L)	4	40
	Leukocytopenia (<3.0 × 10^9/L)	9	90
Outcome	Mortality	0	0