226
Views
1
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Albumin Infusion May Improve the Prognosis of Critical COVID-19 Patients with Hypoalbuminemia in the Intensive Care Unit: A Retrospective Cohort Study

, , , ORCID Icon, , & ORCID Icon show all
Pages 6039-6050 | Received 02 Aug 2022, Accepted 29 Sep 2022, Published online: 19 Oct 2022

Figures & data

Table 1 Comparison of Clinical Features Between Groups

Figure 1 Patient recruitment flow chart.

Figure 1 Patient recruitment flow chart.

Figure 2 Correlation between albumin levels and highest body temperature during hospitalization. There was a significant negative correlation was found between albumin level and highest body temperature during hospitalization (R=−0.29, P=0.045). The solid red line and red dotted lines are the simple linear regression equation and 95% confidence interval, respectively.

Figure 2 Correlation between albumin levels and highest body temperature during hospitalization. There was a significant negative correlation was found between albumin level and highest body temperature during hospitalization (R=−0.29, P=0.045). The solid red line and red dotted lines are the simple linear regression equation and 95% confidence interval, respectively.

Table 2 Comparison of Laboratory Variables Between Groups

Table 3 Associations Between Albumin Concentrations After Infusion and Laboratory Variables

Figure 3 Correlation between albumin levels and IL-6 concentrations. There was a significant negative correlation was found between albumin level and IL-6 (R=−0.35, P=0.012). The solid red line and red dotted lines are the simple linear regression equation and 95% confidence interval, respectively.

Figure 3 Correlation between albumin levels and IL-6 concentrations. There was a significant negative correlation was found between albumin level and IL-6 (R=−0.35, P=0.012). The solid red line and red dotted lines are the simple linear regression equation and 95% confidence interval, respectively.

Table 4 Cox Regression Model Based on Albumin Level After Infusion

Figure 4 Kaplan-Meier survival curves of the non-albumin infusion and albumin infusion groups.

Figure 4 Kaplan-Meier survival curves of the non-albumin infusion and albumin infusion groups.

Figure 5 Kaplan-Meier survival curves of the ≤4 and >4 times infusion groups.

Figure 5 Kaplan-Meier survival curves of the ≤4 and >4 times infusion groups.

Figure 6 Kaplan-Meier survival curves of increased and non-increased groups.

Figure 6 Kaplan-Meier survival curves of increased and non-increased groups.