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Infection and Drug Resistance Volume 15, 2022 - Issue
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ORIGINAL RESEARCH

Analysis of Metagenomic Next-Generation Sequencing Results of 25 Pus Samples

Yuru ShiDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaView further author information
,
Jing WuDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0003-1931-4678View further author information
ORCID Icon,
Ting LiuDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaView further author information
,
Li YueDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaView further author information
,
Yang LiuDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaView further author information
,
Yan GuDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaView further author information
&
Yingjie QiDepartment of Clinical Laboratory, Infection Hospital Area of the First Affiliated Hospital of University of Science and Technology of China (Hefei Infectious Disease Hospital), Hefei, 230022, People’s Republic of ChinaCorrespondence[email protected]
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Pages 6515-6524 | Received 11 Aug 2022, Accepted 27 Oct 2022, Published online: 08 Nov 2022

Figures & data

Table 1 Patient Characteristic Analysis

Table 2 Comparison of Positive Rate Between Two Methods

Table 3 Comparison of mNGS Results with Traditional Culture Results

Figure 1 Comparison of the mNGS results with the traditional detection methods.

Figure 1 Comparison of the mNGS results with the traditional detection methods.

Figure 2 Detection Results of the mNGS.

Figure 2 Detection Results of the mNGS.

Figure 3 Pathogen composition detected by mNGS.

Figure 3 Pathogen composition detected by mNGS.

Figure 4 Proportion of multiple pathogens, detected by mNGS and culture.

Figure 4 Proportion of multiple pathogens, detected by mNGS and culture.

Table 4 The Traditional General Culture Was Negative, and the Use of Antibiotics After the Use of mNGS and Its Outcome

Figure 5 Patient 22 all pathogens detected in pus samples.

Figure 5 Patient 22 all pathogens detected in pus samples.

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