Acute Helicobacter pylori Infection Prevalence Among Renal Failure Patients and Its Potential Roles with Other Chronic Diseases: A Retrospective Cohort Study

Figures & data

Table 1 Distribution of H. pylori Infection Among Dialysis Patient’s Gender

Patient’s Genders	H. pylori (%)		Total	p-value
	ve +	ve -
Male	23 (54.8%)	57(67.1%)	80 (63%)	0.177
Female	19 (45.2%)	28 (32.9%)	47 (37%)
Total	42 (100%)	85 (100%)	127

Table 2 Distribution of H. pylori Among Different Age Groups of Dialysis Patients

Patient’s Genders	H. pylori (%)		Total	p-value
	ve +	ve -
10–20 yrs	0 (0%)	1(1.2%)	1 (0.8%)	0.147
21–30 yrs	11 (26.2%)	8 (9.4%)	19 (15%)
31–40 yrs	5 (11.9%)	11 (12.9%)	16 (12.6%)
41–50 yrs	8 (19%)	23 (27.1%)	31(24.4%)
>51 yrs	18 (42.9%)	42(49.4%)	60 (47.2%)
Total	42 (100%)	85 (100%)	127

Table 3 Distribution of H. pylori Infection with Other Underlying Medical Diseases

Underlying Diseases	H. pylori		Total	p-value
	ve +	ve -
HTN	28 (66.7%)	57 (67.1%)	85 (66.9%)	0.926
DM	2 (4.7%)	4 (4.7%)	6 (4.7%)
HTN & DM	11 (26.2)	20 (23.5%)	31 (24.4%)
Others	1 (2.3%)	4 (4.7%)	5 (3.9%)
Total	42 (100%)	85 (100%)	127

Figure 1 Prevalence of H. pylori acute infection among dialysis patients. (***) p-value: 0.0001.

Figure 2 Distribution of H. pylori seropositivity among different age groups of 42 infected dialysis patients.

Figure 3 Association of H. pylori acute infection with other underlying medical diseases among dialysis patients. (A) Dialysis patients with hypertension (HTN), (B) dialysis patients with hypertension and diabetes mellitus, (C) dialysis patients with diabetes mellitus only (DM), (D) dialysis patients with other underlying medical conditions.

Figure 4 Distribution of different underlying medical diseases among positive H. pylori dialysis patients (p-value: <0.0001).

Table 4 Predictors of Change in H. pylori Infectivity

	B	S.E.	Degree of Freedom	p-value	95% Confidence Interval
Underlying diseases			3	0.918
HTN	−0.675	1.142	1	0.554	0.054 to 4.769
HTN & DM	−0.788	1.179	1	0.504	0.045 to 4.586
DM	−0.693	1.414	1	0.624	0.031 to 7.994

Figure 5 Potential roles of H. pylori infection and its interventions in the cyclic relation between chronic kidney disease (CKD), diabetes mellitus (DM) and hypertension (HTN).