Epidemiological and Clinical Characteristics of Neonatal Ureaplasma urealyticum Infection

Figures & data

Table 1 Basic Detection Rate of Neonates with Ureaplasma urealyticum Infection

	Detective Number	Negative Number	Detective Rate (%)	χ^2	P
Total	561	6696	7.73
Male	309	3929	7.30	2.756	0.097
Female	252	2767	8.35
1–7day	516	5929	8.00	6.384	0.094
8–14day	17	290	5.53
15–21day	17	263	6.07
22–28day	11	214	4.89
Spring	142	1542	8.43	7.165	0.067
Summer	148	1778	7.68
Autumn	158	1713	8.44
Winter	113	1663	6.36

Figure 1 The distribution of Ureaplasma urealyticum positive rate among neonates in different ages.

Figure 2 The distribution of Ureaplasma urealyticum positive rate among neonates in different seasons.

Figure 3 The distribution of Ureaplasma urealyticum positive rate among neonates in different months.

Table 2 Basic Clinical Characteristics of UU-Positive and UU-Negative Neonates

		UU Positive	UU Negative	Z,t/χ^2	P
Sex, n (%)		561	496
	Male	309(55.1)	295(59.5)	2.077	0.15
	Female	252(44.9)	201(40.5)
Gestational age, weeks		34.9±4.5	36.6±2.7	−7.162	<0.001
	<37 weeks	32.0 (29.3~34.0)	34.7 (33.6~35.7)	−12.180	<0.001
	37~42 weeks	39.7 (39.0~40.3)	38.9 (38.1~39.7)	−6.494	<0.001
	≥42 weeks	42	/	/	/
Birth weight, g		2426.4±911.9	2701.5±690.2	−5.473	<0.001
	<1000	890.0(782.5~922.5)	630.0	−1.464	0.143
	1000~1500	1222.5(1142.5~1357.5)	1300.0(1240.0~1415.0)	−1.988	0.047
	1500~2500	2000.0(1730.0~2230.0)	2085(1890.0~2237.5)	−2.202	0.028
	2500~4000	3245.0(3000.0~3500.0)	3150.0(2850.0~3400.0)	−2.98	0.003
	>4000	4115.0 (4050.0~4280.0)	4100.0(4040.0~4275.0)	−0.143	0.886
Delivery mode, n (%)		561	496
	Vaginal delivery	377(67.2)	144(29.0)	153.441	<0.001
	Cesarean section	184(32.8)	352(71.0)
Premature rupture of membranes, n (%)		561	496
	Yes	257(45.8)	94(19.0)	85.625	<0.001
	No	304(54.2)	402(81.0)
Co-pathogen infection, n (%)		561	496
	Yes	47(8.4)	22(4.4)	6.706	<0.01
	No	514(91.6)	474(95.6)
Complication, n (%)		561	496
	Respiratory failure of newborn	337(60.1)	210(42.3)	33.152	<0.001
	Respiratory distress syndrome of newborn	274(48.8)	160(32.3)	29.915	<0.001
	Neonatal pneumonia	102(18.2)	88(17.7)	0.035	0.853
	Bronchopulmonary dysplasia of newborn	78(14.0)	5(1.0)	60.502	<0.001
	Retinopathy prematurity	38(6.8)	6(1.2)	20.428	<0.001
	Necrotizing enterocolitis of the newborn	22(3.9)	10(2.0)	3.256	0.071
	Neonatal meningitis	10(1.8)	2(0.4)	4.462	0.035

Table 3 Gestational Age and Weight Characteristics of Neonates with Ureaplasma urealyticum Infection

	Gestational Age			Birth Weight
	<37 Week	37–42 Week	≥42 Week	<1000g	1000–1500g	1500–2500g	2500–4000g	>4000g
Male	176 (56.96)	132 (42.72)	1 (0.32)	8 (2.59)	57 (18.45)	94 (30.42)	141 (45.63)	9 (2.91)
Female	153 (60.71)	99 (39.29)	0 (0)	10 (3.97)	39 (15.48)	93 (36.90)	107 (42.46)	3 (1.19)
Total	329 (58.64)	231 (41.18)	1 (0.18)	18 (3.21)	96 (17.11)	187 (33.33)	248 (44.21)	12 (2.14)

Table 4 Analysis of Ureaplasma urealyticum-Infected Neonates with Other Pathogens

One Pathogen Infection	Number	Two Pathogens Infection	Number	Three Pathogens Infection	Number	Total
Escherichia coli	9	RSV+CMV	1	CMV+HSV+Treponema pallidum	1
RSV	5	Escherichia coli+Enteroaerogen	1
HSV	3	Escherichia coli+CMV	1
Candida albicans	3	Escherichia coli+RSV	1
HBV	2	Staphylococcus aureus+Candida albicans	1
Acinetobacter junii	2	Staphylococcus aureus+CT	1
Klebsiella pneumoniae	2
Candida glabrata	2
CT	2
Streptococcus agalactiae	2
CMV	1
HCV	1
Staphylococcus aureus	1
Streptococcus gallolyticus	1
Saccharomyces cerevisiae	1
Proteus mirabilis	1
Enteroaerogen	1
Treponema pallidum	1
Sum	40		6		1	47