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Original Research

Procoagulant inhibitory properties of paclitaxel poliglumex

, , , , , & show all
Pages 5-11 | Published online: 15 Dec 2010

Figures & data

Table 1 Time to peak plasma concentration of conjugated taxane with various CT-2103 doses

Table 2 Baseline patient characteristics

Figure 1 Prothrombin time (PT) and activated thromboplastin time (aPTT) values versus CT-2103 concentration.

Figure 1 Prothrombin time (PT) and activated thromboplastin time (aPTT) values versus CT-2103 concentration.

Figure 2 Activated thromboplastin time (aPTT) values over time following CT-2103 administration per patient. Patient identification numbers are shown in the margin.

Figure 2 Activated thromboplastin time (aPTT) values over time following CT-2103 administration per patient. Patient identification numbers are shown in the margin.

Figure 3 Dose-response curve of heparin/antithrombin III complex inhibition of both thrombin and factor Xa activity.

Figure 3 Dose-response curve of heparin/antithrombin III complex inhibition of both thrombin and factor Xa activity.

Table 3 CT-2103 inhibition of α-thrombin activity in heparin assay

Table 4 CT-2103 inhibition of factor Xa activity in heparin assay

Table 5 Factor IIa and Xa inhibition is independent of antithrombin III

Table 6 Raw data for factors IXa, XIa, and XII