Factors predicting the outcomes of elderly hospitalized myasthenia gravis patients: a national database study

Figures & data

Table 1 Factors affecting treatment outcomes in elderly hospitalized myasthenia gravis patients by univariate logistic regression analysis

Factors		Outcomes (n = 441)		Crude OR	95% CI	p-value
		Good n = 375 (%)	Poor n = 66 (%)
Age, years	Mean (SD)	69.6 (7.2)	71.4 (7.3)	1.03	(1.00, 1.07)	0.065
Gender	Male	148 (39.5)	31 (47.0)	1	–
	Female	227 (60.5)	35 (53.0)	1.36	(0.80, 2.30)	0.254
Insurance type	GWME	129 (34.4)	28 (42.4)	1	–
	SSF	16 (4.3)	0 (0.0)
	UC	230 (61.3)	38 (57.6)	0.76	(0.45, 1.30)	0.316
Hospital level	Primary	20 (5.3)	1 (1.5)	1	–	0.266
	Secondary	64 (17.1)	16 (24.2)	5.00	(0.62, 40.09)
	Tertiary	75 (20.0)	14 (21.2)	3.73	(0.46, 30.12)
	Private	216 (57.6)	35 (53.0)	3.24	(0.42, 24.92)
Region	Northern	73 (19.5)	16 (24.2)	1	–	0.489
	Northeast	81 (21.6)	10 (15.2)	0.56	(0.24, 1.32)
	Central	202 (53.9)	35 (53.0)	0.79	(0.41, 1.51)
	Southern	19 (5.1)	5 (7.6)	1.20	(0.39, 3.69)
Pneumoniaa	No	353 (94.1)	46 (69.7)	1	–
	Yes	22 (5.9)	20 (30.3)	6.98	(3.54, 13.76)	<0.001
Respiratory failure	No	342 (91.2)	40 (60.6)	1	–
	Yes	33 (8.8)	26 (39.4)	6.74	(3.66, 12.39)	<0.001
Septicemiaa	No	356 (94.9)	43 (65.2)	1	–
	Yes	19 (5.1)	23 (34.9)	10.02	(5.05, 19.88)	<0.001
Intravenous immunoglobulin	No	356 (94.9)	65 (98.5)	1	–
	Yes	19 (5.1)	1 (1.5)	0.29	(0.04, 2.19)	0.229
Plasmapheresis	No	371 (98.9)	64 (97.0)	1	–
	Yes	4 (1.1)	2 (3.0)	2.90	(0.52, 16.15)	0.225
On continuous invasive MV	No	329 (87.7)	32 (48.5)	1	–
	Yes	46 (12.3)	34 (51.5)	7.60	(4.29, 13.48)	<0.001
Thymectomy	No	362 (96.5)	66 (100.0)
	Yes	13 (3.5)	0 (0.0)
Length of stay, days	Mean (SD)	10.6 (17.7)	15.6 (22.2)	1.01	(1.00, 1.02)	0.054
Hospital charge (× 10,000)	Mean (SD)	5.8 (15.5)	11.2 (17.3)	1.02	(1.00, 1.03)	0.032

Notes: Data presented as number (%), unless indicated otherwise.

a Acquired after admission to hospital. ‘–’ indicates no data.

Abbreviations: OR, odds ratio; CI, confidence interval; GWME, Government Welfare Medical Expense; SSF, Social Security Fund; UC, universal coverage; MV, mechanical ventilator; SD, standard deviation.

Table 2 Significant factors affecting poor treatment outcomes in elderly hospitalized myasthenia gravis patients by multivariate logistic regression analysis

Factors	Adjusted odds ratio	95% confidence interval	p-value
Pneumonia	2.83	1.03, 7.75	0.043
On continuous invasive MV	5.33	2.24, 12.72	<0.001
Septicemia	4.47	1.86, 10.75	0.001

Abbreviation: MV, mechanical ventilator.