Risk of Cardiovascular Disease Mortality in Relation to Depression and 14 Common Risk Factors

Figures & data

Figure 1 Participants enrollment flowchart including exclusion criteria-NHANES 2005–2014.

Table 1 Weighted Baseline Characteristics of the Study Population-NHANES 2005–2014

Variables	Status	Overall			Depression						P value
					Yes			No
		N	%	SE	N	%	SE	N	%	SE
Gender	Male	10,891	48.76	0.33	241	34.02	2.25	10,650	49.18	0.33	<0.01
	Female	11,286	51.24	0.33	487	65.98	2.25	10,799	50.82	0.33
Age	20–39 years	7753	37.05	0.74	216	33.80	2.28	7537	37.14	0.77	<0.01
	40–59 years	7268	38.47	0.51	335	49.80	2.27	6933	38.15	0.52
	60–79 years	5906	20.68	0.50	162	14.44	1.10	5744	20.85	0.51
	≥80 years	1250	3.80	0.18	15	1.96	0.51	1235	3.85	0.19
Race	White	10,483	70.50	1.46	329	63.89	2.72	10,154	70.69	1.46	<0.01
	Black	4680	10.79	0.78	161	14.40	1.63	4519	10.69	0.77
	Others	7014	18.71	1.07	238	21.70	2.21	6776	18.63	1.06
Education	<High school	5424	16.32	0.68	267	27.93	2.13	5157	15.99	0.69	<0.01
	=High school	5110	22.78	0.59	186	28.24	2.29	4924	22.62	0.58
	>High school	11,643	60.90	1.04	275	43.83	2.78	11,368	61.39	1.04
PIR	<1	4605	13.88	0.61	309	33.86	2.19	4296	13.31	0.59	<0.01
	1≤PIR≤median	8063	30.60	0.70	301	40.39	2.06	7762	30.32	0.70
	>Median	9509	55.53	1.05	118	25.76	2.26	9391	56.37	1.04

Abbreviations: PIR, poverty-income ratio; CVD, cardiovascular disease; N, number; %, weighted percent; SE, standard error.

Figure 2 Adjusted dose–response association between BMI/WC and risk for CVD mortality in participants with (A) and without (B) depression. Y-axis represents the adjusted hazard ratio of CVD mortality for a given BMI/WC value compared with a referent level of 5th percentile of its distribution. The model was adjusted for age, sex, race/ethnicity, education and poverty income ratio.

Figure 3 Multivariable-adjusted hazard ratio for CVD mortality by statuses of depression and each of the 14 common risk factors. The model was adjusted for age, sex, race/ethnicity, education, poverty income ratio, smoking, alcohol use, activity, BMI, period, congestive heart failure, coronary heart disease, angina, angina pectoris, heart attack, diabetes, high blood pressure or hypertension, cancer or malignancy of any kind, and stroke.

Figure 4 Survival curves (A) and weighted CVD mortality (B) by statuses of depression and living alone, BMI, WC or baseline CVD.