A case of thrombotic thrombocytopenic purpura induced by acute pancreatitis

Figures & data

Table 1 Laboratory data on pre-admission

Days from diagnosis	day 1	day 2	day 3	day 4
WBC × 10^2/μL	155	NT	232	141
RBC × 10^4/μL	478	NT	360	203
Hb g/dL	10.8	NT	7.5	4.2
PLT × 10^4/μL	45.7	NT	10.2	2.7
AMY U/L	1614	NT	473.5	NT
T-Bil mg/dL	0.34	NT	2.88	NT
D-Bil mg/dL	0.1	1.1	NT	NT
LDH U/L	317	2209	NT	NT
CRTN mg/dL	0.37	NT	2.72	NT
CRP mg/dL	0.28	NT	14.98	NT

Abbreviation: ns: WBC, white blood cells; RBC, red blood cells; Hb, hemoglobin; PLT, platelets; AMY, amylase; T-Bil, total bilirubin; D-Bil, direct bilirubin; LDH, lactate dehydrogenase; CRTN, creatinine; CRP, C-reactive protein; NT, not tested.

Table 2 Laboratory data on admission (= day 5)

WBC	162 × 10^2/μL
RBC	309 × 10^4/μL
Hb	7.4 g/dL
Ht	22.4%
PLT	2.4/μL
schistocytes	3+ (>5%)
AMY	96 U/L
P-AMY	87 U/L
AST	77 U/L
ALT	27 U/L
T-Bil	3 mg/dL
D-Bil	0.8 mg/dL
LDH	2121 U/L
BUN	43 mg/dL
CRTN	2.51 mg/dL
eGFR	17 ml/min/1.73m^2
CRP	14.5 mg/dL
SAA	690 μg/dL
Hp	<10 mg/dL
PT	119%
PT-INR	0.91
APTT	26.1 sec
FBG	316 mg/dL
AT	III 76%
D-Ddimer	8.5 μg/dL
Direct Coombs	(–)

Abbreviations: WBC, white blood cells; RBC, red blood cells; Hb, hemoglobin; PLT, platelets; AMY, amylase; T-Bil, total bilirubin; D-Bil, direct bilirubin; LDH, lactate dehydrogenase; CRTN, creatinine; CRP, C-reactive protein; BUN, blood urea nitrogen; AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, epidermal growth factor receptor; SAA, serum amyloid; Hp, haptoglobin; PT, prothrombin time; PT-INR, prothrombin international normalized ratio; APTT, activated partial thromboplastin time; FBG, fibrinogen; AT III, antithrombin III.

Figure 1 Clincial course of the patient.

Abbreviations: Hb, hemoglobin; PSL, prednisolone; Plt, platelets; RCC, red cell concentrate; PC, platelet cells; FFP, fresh frozen plasma.