Inflammatory status hepatic enzymes and serum creatinine in HIV-, HIV+ and HIV-TB co-infected adult Central Africans

Figures & data

Table 1 Demographic and clinical characteristics of the study population

Variables	Nor mean ± SD	%
Gender
Male	13	25
Female	39	75
Age (years)	37 ± 10.8
Groups
HIV and PTB coinfection	32	61.5
HIV+ and PTB-	10	19.2
PTB+ and HIV-	10	19.2

Abbreviations: HIV, human immunodeficiency virus; PTB, pulmonary tuberculosis; SD, standard deviation.

Table 2 Comparisons of characteristics across the groups without adjusting for age and sex

Variables	HIV+ and PTB+, n = 32 naive	HIV+ and PTB-, n = 10	HIV− and PTB+, n = 10
Age (years)	37 ± 10.8	38 ± 10.5	32 ± 8.5
AST (U/L)	7.7 ± 4.9	8.7 ± 4.5	15.7 ± 10.8
ALT (U/L)	11.2 ± 6.2	27.5 ± 5.5	9.1 ± 8.1
GGT (U/L)	42.5 ± 10	55.6 ± 10.2	32.3 ± 5.1
Creatinine (mg/dL)	0.6 ± 0.3	1.5 ± 0.5	1.3 ± 0.4
CRP (mg/L)	7.6 ± 2.6	22.4 ± 3.4	17.6 ± 2.9

Abbreviations: ALT, alanine transferase; AST, aminotransferase; CRP, C-reactive protein; GGT, gamma-glutamyl transferase; HIV, human immunodeficiency virus; PTB, pulmonary tuberculosis.

Table 3 Comparisons of characteristics across the study groups after adjusting for age and sex

Variables	Naive HIV-PTP coinfection	Naive HIV+	Naive PTB
AST (U/L)	15 ± 5	9 ± 4.8	13.2 ± 9
ALT (U/L)	13.2 ± 5	29.4 ± 7.2	8.3 ± 6.4
GGT (U/L)	44.5 ± 11	59.7 ± 9.5	30 ± 4.9
Creatinine (mg/dL)	1.4 ± 0.4	2.1 ± 0.6	1.2 ± 0.3
CRP (mg/L)	13.8 ± 5.3	45.7 ± 6.9	34.6 ± 4.8

Abbreviations: ALT, alanine transferase; AST, aminotransferase; CRP, C-reactive protein; GGT, gamma-glutamyl transferase; HIV, human immunodeficiency virus; PTB, pulmonary tuberculosis.