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Original Research

Serum Folate and All-Cause Mortality is of Non-Linear Relationship Among Population with Chronic Kidney Disease: A Retrospective Cohort Study

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Pages 2695-2702 | Published online: 21 Jun 2021

Figures & data

Figure 1 Flowchart of participation selection.

Figure 1 Flowchart of participation selection.

Table 1 Baseline Characteristic of the Study Participants with Chronic Kidney Disease (n=2142)

Table 2 Multivariate Analysis of Serum Folate Levels Associated with All-Cause Mortality

Table 3 Threshold Effect Analysis of Serum Folate on Mortality Using Piece-Wise Linear Regression Model

Figure 2 Adjusted restricted cubic spline plots for all-cause mortality and serum folate concentrations. The potential confounders adjusted were as follows: age, sex, race, hypertension, physical activity, body mass index, eGFR, serum vitamin B12, albumin, serum glucose, phosphorus, uric acid, total iron binding capacity, folate as dietary folate equivalents, food folate.

Figure 2 Adjusted restricted cubic spline plots for all-cause mortality and serum folate concentrations. The potential confounders adjusted were as follows: age, sex, race, hypertension, physical activity, body mass index, eGFR, serum vitamin B12, albumin, serum glucose, phosphorus, uric acid, total iron binding capacity, folate as dietary folate equivalents, food folate.

Figure 3 Survival probability by the level of serum folate. Quintile categories of serum folate: Q1<8.7ng/mL, Q2 8.7–11.4ng/mL, Q3 11.5–14.6ng/mL, Q4 14.7–19.1ng/mL, Q5 ≥19.2ng/mL. The potential confounders adjusted were as the same as .

Figure 3 Survival probability by the level of serum folate. Quintile categories of serum folate: Q1<8.7ng/mL, Q2 8.7–11.4ng/mL, Q3 11.5–14.6ng/mL, Q4 14.7–19.1ng/mL, Q5 ≥19.2ng/mL. The potential confounders adjusted were as the same as Figure 2.