Study on the Optic Nerve Fiber Layer Thickness and Changes in Blood Flow in Myopic Children

Figures & data

Table 1 Eye Related Parameters

Characteristics	Emmetrope Group	Mild Myope Group	Moderate Myope Group	High Myope Group	F	P
Gender (M:F)	17/14	34/25	27/31	26/30	0.502	0.681
Age (yr)	9.8±3.0	9.9±2.4	10.7±3.0	10.9±3.2	1.473	0.223
MSE(Diopter)	−0.11±0.36	−1.62±0.68	−4.64±0.79	−7.96±1.99	401.223	0.000
AL (mm)	23.20±0.40	24.13±0.87	25.55±0.69	26.74±0.94	176.031	0.002

Table 2 RPC Density (%)

RPC Density (%)	Emmetrope Group	Mild Myope Group	Moderate Myope Group	High Myope Group	F	P
Optic papillary flow density	52.38±2.75	51.67±2.11	51.91±3.20	49.82±2.70	8.584	0
NS blood flow density	47.93±4.14	47.43±4.17	47.22±4.44	44.82±5.33	4.618	0.004
NI blood flow density	46.72±5.34	45.55±5.02	46.32±4.76	42.04±6.22	8.154	0
IN blood flow density	50.83±4.38	50.52±3.77	50.03±4.84	48.39±4.20	3.185	0.025
IT blood flow density	57.18±3.48	56.82±3.83	57.82±4.26	56.85±4.13	2.675	0.048
TI blood flow density	53.74±3.96	54.34±3.43	54.56±4.26	54.04±5.04	0.306	0.821
TS blood flow density	58.33±3.85	55.78±3.35	55.33±9.05	53.18±10.99	2.952	2.952
ST blood flow density	56.13±2.86	56.29±3.98	56.29±4.34	54.18±4.20	3.672	0.013
SN blood flow density	49.98±3.87	50.19±4.12	50.62±4.27	48.96±4.23	1.623	0.185
Superior quadrant flow density (quadrant IV)	52.65±2.93	51.76±3.28	52.12±4.36	50.89±4.18	1.685	0.171
Nasal quadrant flow density (quadrant IV)	48.03±4.11	48.51±5.43	50.52±6.82	46.93±8.06	3.002	0.032
Inferior quadrant flow density (quadrant IV)	53.42±4.27	54.36±3.85	53.47±4.07	53.20±4.20	4.458	0.005
Temporal quadrant flow density (quadrant IV)	55.74±5.30	52.75±4.00	52.55±6.62	51.13±7.10	4.041	0.008

Abbreviations: NS, nasal superior subregion; NI, nasal inferior subregion; IN, inferior nasal subregion; IT, Inferior temporal subregion; TI, Temporal inferior subregion; TS, Temporal superior subregion; ST, superior temporal subregion; SN, superior nasal subregion.

Table 3 RNFL Thickness (μm)

RNFL Thickness (μm)	Emmetrope Group	Mild Myope Group	Moderate Myope Group	High Myope Group	F	P
Papilla of optic nerve	119.74±8.81	120.08±10.30	119.55±15.13	114.80±13.59	2.154	0.095
NS	109.26±13.47	115.46±18.70	112.14±26.92	104.20±27.00	2.413	0.068
NI	89.39±14.35	91.78±15.66	93.33±24.48	84.25±25.95	1.952	0.122
IN	157.19±22.32	146.69±18.79	134.98±25.66	126.68±24.44	14.584	0
IT	157.42±15.73	158.15±18.62	165.34±21.76	160.34±19.91	1.725	0.163
TI	75.19±9.77	79.58±11.50	86.95±16.87	91.32±17.57	10.753	0
TS	84.26±8.28	82.39±10.53	84.34±16.00	86.00±23.87	0.461	0.71
ST	147.81±21.51	143.36±16.47	151.02±21.61	143.46±22.82	1.824	0.144
SN	149.29±14.14	150.63±20.31	139.36±23.71	133.18±35.60	5.449	0.001
Superior quadrant flow density (quadrant IV)	147.84±9.46	147.39±13.80	144.66±18.37	137.93±23.29	3.422	0.018
Nasal quadrant flow density (quadrant IV)	100.94±13.33	104.97±15.53	103.74±24.78	95.36±25.24	2.327	0.076
Inferior quadrant flow density (quadrant IV)	157.06±12.35	151.56±14.51	148.38±20.27	141.48±16.19	6.806	0
Temporal quadrant flow density (quadrant IV)	79.90±7.50	81.08±9.02	86.36±19.71	90.09±14.78	5.367	0.001

Abbreviations: NS, nasal superior subregion; NI, nasal inferior subregion; IN, inferior nasal subregion; IT, Inferior temporal subregion; TI, Temporal inferior subregion; TS, Temporal superior subregion; ST, superior temporal subregion; SN, superior nasal subregion; RNFL, retinal nerve fiber layer.