Exploring the Potential Key IncRNAs with Endometriosis by Construction of a ceRNA Network

Figures & data

Table 1 Details of the lncRNA-Associated ceRNA Networks and Significant Ternary Relationships

Network	Type	Number in Network 1	Number in Network 2
LncRNA-associated ceRNA network	lncRNA–mRNA interactions	14,137	4459
	lncRNA	242	111
	miRNA	55	39
	mRNA	1660	1151
Significant ternary relationship	lncRNA–mRNA interactions	666	197
	lncRNA	107	22
	miRNA	40	22
	mRNA	274	136

Figure 1 Constructed lncRNA-associated ceRNA network. Orange represents lncRNA, green represents miRNA, blue represents mRNA.

Figure 2 Functional enrichment analysis of mRNA for two networks. (A) Functional enrichment analysis for network 1. (B) Functional enrichment analysis for network 2.

Figure 3 Network visualization of significant ternary relationships and degree of lncRNA and mRNA in significant ternary relationships. (A) Network visualization of significant ternary relationship for module 1. (B) Network visualization of significant ternary relationship for module 2. (C) Degree of lncRNA and mRNA in significant ternary relationship for module 1. (D) Degree of lncRNA and mRNA in significant ternary relationship for module 2.

Figure 4 Subnetwork of top six degrees of lncRNA in significant ternary relationships and functional enrichment analysis with top six degrees of lncRNA related mRNAs. (A) Subnetwork of top six degrees of lncRNA in significant ternary relationship for module 1 (B) Functional enrichment analysis with top six degrees of lncRNA related mRNAs for module 1. (C) Subnetwork of top six degrees of lncRNA in significant ternary relationship for module 2. (D) Functional enrichment analysis with top six degrees of lncRNA related mRNAs for module 2.