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Original Research

Efficacy and Safety of Regorafenib Monotherapy among Patients with Previously Treated Metastatic Colorectal Cancer in a Chinese Population: A Real-World Exploratory Study

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Pages 5363-5373 | Published online: 07 Sep 2021

Figures & data

Table 1 Baseline Characteristics of Patients with Metastatic CRC According to Hypertension and HFS Status

Figure 1 Waterfall plot of best percentage change in target-lesion size among atients with previously treated metastatic colorectal cancer.

Figure 1 Waterfall plot of best percentage change in target-lesion size among atients with previously treated metastatic colorectal cancer.

Figure 2 MRI scan results of change in target lesions in liver metastasis of one patient with metastatic colorectal cancer after treatment with regorafenib.

Figure 2 MRI scan results of change in target lesions in liver metastasis of one patient with metastatic colorectal cancer after treatment with regorafenib.

Figure 3 Progression-free survivaland overall survival of patients with previously treated metastatic colorectal cancer.

Figure 3 Progression-free survivaland overall survival of patients with previously treated metastatic colorectal cancer.

Table 2 Univariate PFS Analysis of Patients with Metastatic CRC According to Baseline Characteristics

Table 3 Safety Profile of Patients with Metastatic CRC Treated with Regorafenib

Figure 4 Progression-free survival of patients with previously treated metastatic colorectal cancer by hand–foot syndrome status.

Figure 4 Progression-free survival of patients with previously treated metastatic colorectal cancer by hand–foot syndrome status.

Figure 5 Progression-free survival of patients with previously treated metastatic colorectal cancer by hypertension status.

Figure 5 Progression-free survival of patients with previously treated metastatic colorectal cancer by hypertension status.

Table 4 Multivariate Cox Regression Analysis of PFS According to Baseline Characteristics and Adverse-Reaction Status