Electrocardiographic Changes in Dengue Fever: A Review of Literature

Figures & data

Figure 1 Proposed pathogenesis of conduction abnormalities in dengue fever.

Table 1 Studies of Conduction Abnormalities in Dengue Fever

Reference	Study Setting	n	Country	Electrocardiographic Manifestations
Krishna et al^Citation16 (2021)	Hospitalized patients, Adults and older children	108	INDIA	Abnormal ECG in 48.14% patients Sinus bradycardia – 31.48% ST-T changes – 11.1% Sinus tachycardia – 3.7% RBBB – 1.85%
Shah et al^Citation4 (2021)	Hospitalized patients, Adults above age of 18 years	320	INDIA	ECG abnormalities noted in 35% subjects. Sinus bradycardia – 19.7% Sinus Tachycardia – 6.9% 1st Degree AV Block – 1.9% 2nd Degree AV Block – 0.3% Complete Heart Block – 0.6% Atrial fibrillation – 3.75% ST elevation – 1.2% Ventricular tachycardia – 1.8%
Papalkar et al^Citation21 (2019)	Hospitalized patients, Adults and older children	60	INDIA	ECG abnormality noted in 35% patients Sinus bradycardia – 15% Sinus tachycardia – 10% ST-T changes – 8.33% PR prolongation – 1.67%
Poornima and John^Citation3 (2019)	Hospitalized patients, Adults and children	341	INDIA	Abnormal ECG changes noted in 72 patients (21.11%) Sinus bradycardia – 8.79% T wave inversion – 4.1% ST depression – 2.3% AV block – 2.34% Atrial fibrillation – 2.93% Junctional rhythm – 1.15% Supraventricular tachycardia – 0.58% Ventricular ectopics – 1.75%
Datta and Mitra^Citation22 (2019)	Hospitalized patients, Adults and older children	110	INDIA	ECG abnormality noted in 8.2% patients Sinus bradycardia – 3.7% Junctional bradycardia – 2.7% AV block – 0.9% Atrial fibrillation – 0.9%
Kumar and Yadav^Citation23 (2017)	Hospitalized patients, Adults	100	INDIA	ECG abnormalities noted in 87% subjects Sinus bradycardia – 60% Sinus tachycardia – 27% Ventricular ectopics – 15% 1st degree AV Block – 11%
Arora and Patil^Citation24 (2016)	Hospitalized patients	120	INDIA	ECG abnormalities seen in 20% patients Sinus bradycardia – 8.3% Sinus tachycardia – 3.3% ST-T changes – 3.3% 1st Degree AV block – 3.3% Right bundle branch block – 1.6%
Yacoub et al^Citation25 (2012)	Hospitalized patients, Adults and children	79	VIETNAM	ECG abnormalities noted in 35% subjects including 1st degree AV block, sinus bradycardia, T wave changes and ST segment abnormalities
La-Orkhun et al^Citation26 (2011)	Hospitalized children, During convalescent phase of dengue infection	35	THAILAND	ECG abnormalities noted in 29% patients Sinus Pause – 2.9% PVC – 14.3% PAC – 11.4% 1st Degree AV Block – 5.7% 2nd Degree AV Block – 8.6%
Kularatne et al^Citation27 (2007)	Hospitalized patients, Adults and children	120	SRI LANKA	ECG changes noted in 62.5% patients including sinus bradycardia, sinus tachycardia, T wave inversions, ST-segment changes and Right bundle branch block
Wali et al^Citation20 (1998)	Hospitalized patients, Adults and children	17	INDIA	ECG changes noted in 47% patients Sinus bradycardia – 17.6% patients ST-T changes – 29.4%

Figure 2 Algorithm of evaluation and management of conduction abnormalities in dengue fever.

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