Predictive Value of Red Cell Distribution Width in the Diagnosis of Peripherally Inserted Central Catheter (PICC)-Related Thrombosis Among Cancer Patients

Figures & data

Table 1 The General Condition of the Thrombosis Group and the Nonthrombotic Group and the Results of Red Blood Cells and Platelet-Related Indicators ()

Item	Thrombosis Group (n=47)	Nonthrombotic Group (n=51)	t	P
Age (years)	55.36±11.91	50.52±12.35	1.96	0.06
Gender (n)	25 (53.19%)	26 (50.98%)	0.00	0.99
BMI (kg/m^2)	24.32±3.89	24.10±3.75	0.30	0.77
Smoking history (n)	18 (38.30%)	5 (9.80%)	10.73	0.001
Drinking history (n)	6 (12.77%)	6 (11.76%)	0.01	0.91
Hypertension history (n)	12 (25.53%)	10 (19.61%)	0.42	0.52
Diabetes history (n)	1 (2.13%)	4 (7.84%)	1.71	0.19
Test result
HGB (g/L)	114.23±16.43	123.56±15.47	−2.88	0.005
MCV (fL)	95.94±7.15	91.51±7.18	3.05	0.003
RDW (%)	15.98±1.93	13.98±1.09	6.22	<0.001
PLT (10^9/L)	226.744±93.20	233.64±68.58	−0.41	0.68
MPV (fL)	8.60±1.00	8.87±0.96	−1.36	0.18
PDW (%)	15.89±1.09	15.40±1.79	1.65	0.10
PCT	0.19±0.70	0.20±0.06	−1.06	0.29
Tumor category				0.39
Lung cancer	2	3
Hepatobiliary and pancreatic tumors	8	3
Tumors of digestive system	27	34
Breast cancer	2	1
Gynecological tumors	1	2
Retroperitoneal masses	3	4
Others	4	4

Table 2 Logistic Regression Between the Thrombosis and Nonthrombosis Groups

Item	B	Wald	P value	OR
Smoking	1.730	5.136	0.023	5.640
RDW	1.108	21.274	<0.001	3.028

Figure 1 ROC curves of smoking history and RDW in predicting PICC-related thrombosis.

Table 3 Cox Proportional Hazards Model of PICC-Related Thrombosis in 98 Patients

	Univariate Analysis			Multivariate Analysis
Item	P value	Hazard ratio	95% CI	P value	Hazard ratio	95% CI
Smoking history	<0.001	2.593	1.627–5.358	0.028	1.973	1.077–3.615
RDW	<0.001	9.392	3.694–23.877	<0.001	13.059	4.805–35.491

Figure 2 Kaplan‒Meier survival curve of the two RDW groups.

Table 4 Comparison of Baseline RDW and ΔRDW Between the Thrombosis Group and the Nonthrombotic Group ()

Item	Thrombosis group (n=47)	Nonthrombotic group (n=51)	t	P
Baseline-RDW (%)	13.15±1.04	13.07±0.88	0.43	0.09
ΔRDW (%)	2.68±1.64	0.91±1.17	6.14	<0.001